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Pilonidal Sinus clinical trials

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NCT ID: NCT04572919 Completed - Pilonidal Sinus Clinical Trials

Lateral Advancement Flap Versus Classic Limberg Flap in The Treatment Of NonComplicated Pilonidal Sinus

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Background The flaps closure including natal cleft obliteration and eccentric closure are becoming more popular due to their lower rate of recurrence including both the lateral advancement adipo-fascio-cutaneous flap and the classic limberg flap. Objective This study was aim to compare the results of the surgery for non-complicated pilonidal sinus with the lateral advancement adipo-fascio-cutaneous flap versus the classic Limberg flap. Patients and methods This study was a prospective randomized controlled, and was conducted on patients with non-complicated pilonidal sinus attending Zagazig University Hospitals, Egypt during the period from February 2017 to August 2019. Patients were randomly assigned to undergo either lateral advancement flap or classic Limberg flap groups. The follow-up period ranged from 12 to 36 months. Patient satisfaction, complications and recurrence rates were analyzed and compared.

NCT ID: NCT04560049 Recruiting - Clinical trials for Pilonidal Sinus Without Abscess

Phenol and Silver Nitrate Application in Pilonidal Sinus

Start date: June 3, 2020
Phase: Phase 4
Study type: Interventional

Pilonidal sinus is a disease that affects the young population. Wound healing is a problem after surgical interventions Especially wound healing brings minimally invasive interventions to the fore. In this study we will administer two types of irritating agent for pilonidal sinus disesase. One of them is phenol and second one is silver nitrate solution. And not routinely used for pilonidal sinus disease. The data about availeble in pubmed and google scholar is limited focused on silver nitrate The goal of the study is to compare the silver nitrate and phenol application

NCT ID: NCT04430413 Completed - Clinical trials for Pilonidal Disease of Natal Cleft

Effect of Platelet Rich Plasma on Healing of Operated Pilonidal Sinus by Open Method

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to assess the healing promotion effect of platelet rich plasma in patient being operated for sacrococcygeal pilonidal sinus disease by open excision

NCT ID: NCT04423510 Completed - Pilonidal Sinus Clinical Trials

Nonoperative Treatment of Recurrent Pilonidal Sinus Disease

Start date: March 1, 1995
Phase:
Study type: Observational

Postoperative recurrent pilonidal sinus disease is troublesome and its treatment is challenge. Many treatment modalities have been advocated in the treatment of recurrent pilonidal sinus disease; however, there is still no consensus in the literature. Some minimally invasive techniques are used alone or as an adjunct to surgery. Crystallized phenol is the most popular method in the nonoperative treatment of primer pilonidal sinus disease. But its long term effect in the postoperative recurrent cases is unclear. Investigators aimed to present the long-term efficacy of crystallized phenol treatment on postoperative recurrent pilonidal sinus disease through our results collected within the last 20 years.

NCT ID: NCT04418336 Recruiting - Pilonidal Sinus Clinical Trials

Endoscopic Pilonidal Sinus Treatment (EPSIT) Versus Sinus Laser Closure (SiLaC) Versus Lay Open Technique

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Aim of the work To compare Sinus Laser closure versus lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing time and return to daily activity.

NCT ID: NCT04418310 Recruiting - Clinical trials for Endoscopic Pilonidal Sinus

Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease

Start date: June 12, 2020
Phase: N/A
Study type: Interventional

Aim of the work To compare lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing time and return to daily activity

NCT ID: NCT04356768 Completed - Pathology Clinical Trials

Histological Analysis of Sacrococcygeal Pilonidal Sinus Specimens

Start date: March 1, 2020
Phase:
Study type: Observational

Minimally invasive techniques have been widely used routinely and reliably in the treatment of pilonidal sinus. In some of these methods, the cavity of sinus remains in the patient; this condition caused us to question the necessity of pathological examination. Except for prolonged duration of disease, elderly age, macroscopic suspicion, and recurrence; We think that routine pathological examination of the pilonidal sinus is unnecessary.

NCT ID: NCT04273997 Not yet recruiting - Pilonidal Sinus Clinical Trials

Metronidazole Ointment in Non-healing Pilonidal Sinus Wounds

Start date: October 1, 2021
Phase: Phase 2
Study type: Interventional

Title of Study: Randomised, double-blind, placebo-controlled trial evaluating the effects of metronidazole ointment in facilitating resolution on non-healing pilonidal sinus wounds Medical Condition Under Investigation Non-healing pilonidal sinus wounds Study centres: 2 Centres in Turkey Clinical Phase: Phase 2 Protocol Number: MET-PS-02 Study Design: Randomised, double-blind, placebo-controlled, parallel group study to determine the safety and efficacy of metronidazole ointment applied to the wound, following debridement in non-healing pilonidal sinus wounds. Planned Sample Size: 80 subjects

NCT ID: NCT04217824 Recruiting - Clinical trials for Postoperative Complications

Comparison of Karydakis and Limberg Flap Treatment of Pilonidal Sinus in Adolescent. a Prospective, Randomised Study

Start date: May 22, 2019
Phase: N/A
Study type: Interventional

Pilonidal sinus disease (PSD) is a chronic inflammation and infection of the sacrococcygeal region. Produces clinic findings with abscess and discharge in the sacrococcygeal region or painful sinus tract in the natal cleft. Its incidence rate among Turkish servicemen is reported to be 8.8% in a study. Although pilonidal sinus disease is common in men, this is the opposite in adolescence. Because adolescent girls are 2 or 3 times more. Karydakis flap and Limberg flap operations widely preferred in recent years in the surgical treatment of PSD. In our study, we aim to compare these two techniques prospectively and randomly.

NCT ID: NCT04017260 Completed - Pilonidal Sinus Clinical Trials

Combined Open and Closed Approach for Management of Pilonidal Sinus by Special U-shaped Sutures Without Drain.

Start date: December 1, 2015
Phase: N/A
Study type: Interventional

Introduction: Pilonidal sinus disease (PSD) is a common surgical disease frequently seen in the intergluteal cleft. The treatment of this problem is mainly surgical. Aim: introduce a novel technique of combined open and closed approach for management of primary pilonidal sinus (non-recurrent) by special U-shaped sutures and compare it with other techniques as regard operative time, time of complete wound healing, postoperative pain , time to stop analgesic drugs and evaluate the result of surgery without drain. Patients: this study was conducted on 160 patients with PSD in the sacrococcygeal region who underwent operation between December 2015 and December 2017. All cases are divided randomly into four groups each consists of 40 patients.