Pigmentary Retinopathy Clinical Trial
Official title:
Design of a Mobility Protocol to Assess the Impact of Visual Pathologies in Daily Life Activities for Subjects With Advanced Visual Deficits
Retinitis Pigmentosa is characterized by a progressive disappearance of photoreceptors,
responsible for a progressive and severe loss of vision.
People Retinitis Pigmentosa therefore encounter a large number of difficulties in daily life,
specifically for:
- Visual research
- Visuo-motor coordination in tasks requiring fine motor control
- Visuo-motor coordination in mobility tasks
This study aims to assess the difficulties in the daily life of subjects with Retinitis
Pigmentosa at a very advanced stage unsing, quaify of life questionnaires, simplified
locomotion tasks in real situation and a posture task.
They are proposing a new test adapted and carried out in real situations, in binocular and
monocular vision, making it possible to finely assess locomotion especially for "very low
vision" patients.
This test will also ultimately make it possible to better evaluate the effectivements, that
is to say to observe and quantify objectively by a score the performance progression obtained
for locomotion tasks related to the visual recovery generated by the treatment.
This is monocentric study and the total duration of the study is 48 months. The duration of
participation for each research subject is 3 months and maximum 4 visits. This is research
involving the human type of non-invasive interventional research, with minimal risks and
constraints.
This exploratory study will be conducted on a group of patients with Retinitis Pigmentosa at
a very advanced stage.
There will be an inclusion visit including a visual assessment and an ophthalmological
consultation. Two experimental visits with tests carried out in a real environment including
a locomotion and a posture tasks. An end-of-study visit within a maximum of 1 month following
the second experimental visit.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05179460 -
A Study of Pentosan Polysulfate Sodium and the Development of Pigmentary Maculopathy and Pigmentary Retinopathy
|
||
| Recruiting |
NCT04360291 -
Impact of Visual Field Restriction on Visual Exploration
|
||
| Recruiting |
NCT05643157 -
Cellular Scale Measures of Short-Term Retinal Atrophy Progression
|
||
| Recruiting |
NCT03510234 -
Self-confidence Study in Patients With Argus II Artificial Retina
|