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Clinical Trial Summary

Congenital retrognathia, with or without Pierre Robin Sequence (PRS), is a rare anomaly which can be associated with chromosomal abnormalities. Respiratory and feeding consequences can be present at birth. After birth, the diagnosis of retrognathia is based on the clinical examination. Cephalometry can be used to complete the diagnosis. Several authors have proposed the use of objective quantitative ultrasound parameters for the antenatal screening of PRS. In our study, the investigators evaluated fetal cephalometry.

The aim First, the investigators studied the inter- and intra-observer reproducibility of cephalometry. Second, the investigators established reference values for antenatal cephalometry in normal fetuses. Third, the investigators compared the diagnostic performance of cephalometry and the other angles described in the literature for the diagnosis of retrognathia.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04422067
Study type Observational
Source University Hospital, Montpellier
Contact
Status Completed
Phase
Start date May 1, 2019
Completion date September 30, 2019

See also
  Status Clinical Trial Phase
Completed NCT03423017 - Brainstem Dysfunction Involvement in the Pathogenesis of Pierre Robin Sequence N/A
Withdrawn NCT02432638 - Pierre Robin Sequence Outcome Assessment Multi Institutional Study N/A