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NCT01685307 Clinical Trial

Impact of Cooking Process on Meat Protein Digestion and Metabolism

Physiology Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01685307
Other study ID # PRONUTRIAL
Secondary ID
Status Recruiting
Phase N/A
First received March 21, 2012
Last updated September 11, 2012
Start date February 2012

Study information
Verified date September 2012
Source Institut National de la Recherche Agronomique
Contact Gheorghe Airinei, MD
Phone 33 1 48 95 74 30
Email gheorghe.airinei@avc.aphp.fr
Is FDA regulated No
Health authority France: Ministry of Health
Study type Interventional

Clinical Trial Summary

Few is known on meat protein digestibility in humans and the impact of cooking process, while excessive intake of processed meat has been suggested to increase the risk of colorectal cancer.

This study aims to measure in vivo in humans the real digestibility of beef meat proteins depending 2 cooking processes, using ileal tubes and stable isotopes.

Recruitment information / eligibility
Status Recruiting
Enrollment 48
Est. completion date
Est. primary completion date September 2012
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 45 Years
Eligibility Inclusion Criteria:

- Healthy

- BMI between 18 an 27

- Age between 18 and 45 years

Exclusion Criteria:

- Gastrointestinal or liver pathology

- Diabetes

- Pregnancy

- Vegetarian

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Intervention

Dietary Supplement:
• Test meal
test meal is 150 g of beef cooked either at moderate or high intensity. Proteins are intrinsically labelled with 15N.

Locations
Country Name City State
France Centre de Recherche sur volontaires Bobigny

Sponsors (2)
Lead Sponsor Collaborator
Institut National de la Recherche Agronomique National Research Agency, France

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary protein digestibility From ileal recovery of the ingested tracer during 8 h after the meal single measure No
Secondary nitrogen metabolism Distribution of dietary nitrogen throug metabolic pools single measure No
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