Run, Recovery, Repeat, Always Healthy ("Corre, Recupera, Repite, Siempre Saludable")

Physical Exertion Clinical Trial

— CRS  

Official title:

"Corre, Recupera, Repite, Siempre Saludable".

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03155633
• Other study ID #: UJI_CRS001
• Status: Completed
• Phase: N/A
• First received: April 26, 2017
• Last updated: May 15, 2017
• Start date: June 1, 2016
• Est. completion date: November 30, 2016

Study information

• Verified date: May 2017
• Source: Universitat Jaume I
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study has as main objective to know how the processes of recovery are realized after a race of marathon. For this, the participants of a marathon race are divided into three work groups during the 9 days post-marathon, one with rest in the recovery period, another with continuous race three sessions every 48h and another with three sessions of elliptical every 48h .

Description:

The marathon runners suffer a high fatigue, as has been studied by different investigations, the proposal of this study is to know how the recovery processes are produced in runners who have completed a 42km test.

To do this, baseline measurements of the runners have been made through stress tests and determinations of biomarkers in blood and urine. Subsequently blood and urine samples were taken the day before the marathon test and blood and urine samples were then taken again on arrival at 24h, 48h, 96h, 144h, and 196h.

At the same time, an intervention was carried out in the recovery phase, with the runners in three groups. The first one performed rests during the 9 days after the race, the second performed continuous race monitored every 48h from the end of the race, and the third group performed aerobic work on an elliptical machine under the same conditions as the group of Continuous race

Recruitment information / eligibility

• Status: Completed
• Enrollment: 98
• Est. completion date: November 30, 2016
• Est. primary completion date: October 20, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 30 Years to 45 Years

Eligibility

Inclusion Criteria:

• Adults healthy with 30-45 years

• BMI between 16-24,99

• Time in marathon between 3h-4h in men

• Time in marathon between 3h:30min-4h:40min in women

Exclusion Criteria:

• Having heart disease

• Having kidney disease

• Taking a medication on an ongoing basis

Related Conditions & MeSH terms

• Physical Exertion

Intervention

Other:
• Athletics track
Running at 95-105% aerobic Threshold on athletics track 48h, 96h, 144h after the race. Control heart devices
• Elliptical machine
Running at 95-105% aerobic Threshold on elliptical machine 48h, 96h, 144h after the race. Control heart devices

Locations

Country	Name	City	State
n/a

Sponsors (4)

Lead Sponsor	Collaborator
Universitat Jaume I	Fundación Hospitales NISA, Fundación Trinidad Alfonso, SD. Correcaminos

References & Publications (8)

Kim YJ, Ahn JK, Shin KA, Kim CH, Lee YH, Park KM. Correlation of Cardiac Markers and Biomarkers With Blood Pressure of Middle-Aged Marathon Runners. J Clin Hypertens (Greenwich). 2015 Nov;17(11):868-73. doi: 10.1111/jch.12591. Epub 2015 Jun 13. — View Citation

Knechtle B, Knechtle P, Barandun U, Rosemann T, Lepers R. Predictor variables for half marathon race time in recreational female runners. Clinics (Sao Paulo). 2011;66(2):287-91. — View Citation

Knechtle B, Knechtle P, Rosemann T, Lepers R. Personal best marathon time and longest training run, not anthropometry, predict performance in recreational 24-hour ultrarunners. J Strength Cond Res. 2011 Aug;25(8):2212-8. doi: 10.1519/JSC.0b013e3181f6b0c7. — View Citation

Knechtle B, Nikolaidis PT, Zingg MA, Rosemann T, Rüst CA. Differences in age of peak marathon performance between mountain and city marathon running - The ‘Jungfrau Marathon’ in Switzerland. Chin J Physiol. 2017 Feb 28;60(1):11-22. — View Citation

Niemelä M, Kangastupa P, Niemelä O, Bloigu R, Juvonen T. Individual responses in biomarkers of health after marathon and half-marathon running: is age a factor in troponin changes? Scand J Clin Lab Invest. 2016 Nov;76(7):575-580. Epub 2016 Sep 9. — View Citation

Roca E, Nescolarde L, Lupón J, Barallat J, Januzzi JL, Liu P, Cruz Pastor M, Bayes-Genis A. The Dynamics of Cardiovascular Biomarkers in non-Elite Marathon Runners. J Cardiovasc Transl Res. 2017 Apr 5. doi: 10.1007/s12265-017-9744-2. [Epub ahead of print] — View Citation

Santos VC, Sierra AP, Oliveira R, Caçula KG, Momesso CM, Sato FT, Silva MB, Oliveira HH, Passos ME, de Souza DR, Gondim OS, Benetti M, Levada-Pires AC, Ghorayeb N, Kiss MA, Gorjão R, Pithon-Curi TC, Cury-Boaventura MF. Marathon Race Affects Neutrophil Surface Molecules: Role of Inflammatory Mediators. PLoS One. 2016 Dec 2;11(12):e0166687. doi: 10.1371/journal.pone.0166687. eCollection 2016. — View Citation

Tojima M, Noma K, Torii S. Changes in serum creatine kinase, leg muscle tightness, and delayed onset muscle soreness after a full marathon race. J Sports Med Phys Fitness. 2016 Jun;56(6):782-8. Epub 2015 Feb 10. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in the Blood Physiological parameters	Blood test	baseline, 0, 24, 48, 96, 144 and 192 hours post-race
Primary	Analysis of tne changes in the Physical activity data	Physical activity measured by wearing accelerometer devices. Physical activity defined as sedentary, light, moderate and vigorous. The aim to wear accelerometers devices is to monitor individuals during recovery time post-marathon race	One month before the pre-race, accelerometers were worn during seven days. Accelerometers were also worn during nine days starting from the night before the marathon race
Primary	Change in the Urin Physiological parameters	Urin test	baseline, 0, 48, 96, 144 and 192 hours post-race
Secondary	Self-reported questionnaire	Personal questionnaire asking for social and training habits	One month before the race day
Secondary	Strength level	Squat Jump (cm). Two jumps per person	pre-marathon race and 0, 48, 96, 144 hours post-marathon race
Secondary	Analysis of the change of body mass index	BMI	one month before the marathon race day, 24 hours before the marathon race, 2 hours before the marathon race and 10 minutes after the marathon race
Secondary	Physical Condition	Maximal oxygen consumption	One month before the marathon race day
Secondary	Body composition	Bioimpedance analysis	One month before the marathon race day
Secondary	Heart rate	Recording the number of contractions of the heart per minute (bpm) by using a heart rate monitor during all the marathon race	Through marathon completion, an average of 4 hours

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