Skin Aging in Renal Transplant Patients

Photosensitivity Disorders Clinical Trial

Official title:

Skin Aging in Renal Transplant Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01776983
• Other study ID #: 2008SIA01
• Status: Completed
• Phase: Phase 4
• First received: January 24, 2013
• Last updated: June 15, 2015
• Start date: September 2008
• Est. completion date: January 2014

Study information

• Verified date: June 2015
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Determination of collagen, pigment and haemoglobin content of sun exposed and sun protected skin by Siascopy. Immunocompromised patients (for more than seven years) compared to immunocompetent patients.

• Trial in the field of transplantation / xenotransplantation

Description:

Determination of collagen, pigment and haemoglobin content of sun exposed and sun protected skin by Siascopy. Immunocompromised patients (for more than seven years) compared to immunocompetent patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: January 2014
• Est. primary completion date: November 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion criteria:

• Renal transplant recipients transplanted more than seven years ago and immunocompetent probands of the same age.

Exclusion criteria:

• Refusal of informed consent, physical or psychological inability to give informed consent.

Related Conditions & MeSH terms

• Photosensitivity Disorders

Intervention

Device:
• Photosensitivity under the influence of immunocomp
Siascopy measurement of reflected light

Locations

Country	Name	City	State
Switzerland	University Hospital Zurich, Department of Dermatology	Zurich	ZH

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland, 

References & Publications (1)

Stimpfle DW, Serra AL, Wüthrich RP, French LE, Braun RP, Hofbauer GF. Spectophotometric intracutaneous analysis: an investigation on photodamaged skin of immunocompromised patients. J Eur Acad Dermatol Venereol. 2015 Jun;29(6):1141-7. doi: 10.1111/jdv.127 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	skin aging defined by melanin, collagen and hemoglobin content	there is only one time point for measurement, there is no "time frame", just one single measurement per patient at the one and only visit	One Time measurement at the one and only time point of inclusion and measurement