A Study to Evaluate the Pharmacodynamic Activity of E2082 in Adult Participants With Photosensitive Epilepsy

Photosensitive Epilepsy Clinical Trial

Official title:
A Multicenter, Double-Blind, Randomized, Crossover, Single-Dose Study With An Open-Label Treatment Period Evaluating Pharmacodynamic Activity of E2082 in Adult Subjects With Photosensitive Epilepsy

Status Terminated

Clinical Trial Summary

The primary purpose of the study is to assess pharmacodynamic (PD) activity of E2082 as measured by suppression of epileptic photoparoxysmal response (PPR) in the participant's most sensitive eye condition in participants with photosensitive epilepsy, compared to placebo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03686033
Study type	Interventional
Source	Eisai Inc.
Contact
Status	Terminated
Phase	Phase 2
Start date	October 31, 2018
Completion date	June 18, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03239691` - A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients	Phase 2
Completed	`NCT00784212` - Effect of BGG492 on EEG in Patients With Photosensitive Epilepsy	Phase 2
Completed	`NCT00579384` - A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy	Phase 2
Active, not recruiting	`NCT03790137` - Treatment of Sunflower Syndrome With ZX008 (Fenfluramine Hydrochloride) in Children and Young Adults (Ages 4-25).	Phase 3
Completed	`NCT00894010` - Photosensitivity Proof of Concept Trial	Phase 2
Completed	`NCT03580707` - Does BRV Have Faster Onset Time & Greater Effect Than LEV in Epilepsy Pts Using PPR Pharmacodynamic Efficacy Endpoint	Phase 2/Phase 3
Terminated	`NCT03603639` - A Study to Evaluate the Pharmacodynamic Activity of E2730 in Adult Participants With Photosensitive Epilepsy	Phase 2
Completed	`NCT00609245` - Effect of Valproic Acid Concentration on Photic Response	N/A