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A Research Study of How Teens With and Without an Anxiety Disorder Make Decisions

Anxiety Disorders Clinical Trial

Official title:
Decision-Making Processes and Brain Function in Anxiety-Disordered and Non-Anxious Youth

Clinical Trial Summary

The purpose of this trial is to study how teens with and without an anxiety disorder make decisions.

This is a brain imaging study using functional magnetic resonance imaging (fMRI) in adolescents between the ages of 13 and 17.

Clinical Trial Description

Preliminary analyses of behavioral data showed no group differences in response times during the decision-making games. However, behavioral ratings of certainty during the task showed differences between groups. Anxiety-disordered participants indicated lower levels of certainty during the most uncertain conditions of the task (p < .05). This difference was consistent with the study hypothesis. Within-subjects analyses of the decision-making tasks showed that subjects responded as expected. Reaction times (RT) during uncertain conditions of the HiLo-Game were significantly longer than during more certain conditions (p = .001). Diary Task RTs for rating ambiguous situations were significantly longer than ratings of unambiguous situations (p = .019). Preliminary Analyses showed a significant correlation between Intolerance of Uncertainty (IU) and RT during the Marble Task (r = -0.54, p < .05). Preliminary analysis also showed significant correlation between ratings of level of anxiety during the diary task and IU, IS, MASC and the child version of the SCARED. These preliminary results were not submitted for publication. ;

Study Design

Observational Model: Case Control

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00104195
Study type Observational
Source New York University School of Medicine
Contact
Status Completed
Phase Phase 1
Start date February 2004
Completion date April 2014
View Details
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