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Pharyngectomy clinical trials

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NCT ID: NCT03171558 Recruiting - Clinical trials for Head and Neck Neoplasms

Gastric Pull up Versus Free Flap Reconstruction for Laryngo-pharyngeal Defects

GPU vs ALT
Start date: March 16, 2017
Phase: N/A
Study type: Interventional

This study will compare the gastric pull up (GPU) with the free flap [(specifically, anterolateral thigh (ALT) and radial forearm free flap (RFFF)] techniques used in the reconstruction of alimentary tracts in patients who require laryngectomy and circumferential pharyngectomy for carcinoma resection. These two interventions will be compared by block randomizing 20 patients based on history of failed chemoradiation to undergo either ALT or RFFF. The primary outcome will be the type and number of postoperative complications. The secondary outcomes will include swallowing function, speech, and quality of life measures along with cancer specific endpoints.