Pharmacological Action Clinical Trial
Official title:
Redox Interactions Between Dental Restorations and Gingival Crevicular Fluid
The goal of the study was to ascertain the influence of dental caries and teeth position as well as the type and amount of the applied dental materials (DMs) on the oxidative stress (OS) status in gingival crevicular fluid (GCF).
Six DMs were tested by investigators, each sealed in one session: amalgam (Amg), zinc
phosphate cement (ZnPhC), zinc polycarboxylate cement (ZnPoC), glass ionomer cement (GIC) and
composites, Tetric EvoCeram (TEC) and Beautifil (BF).
The study included 88 dental outpatients. Oxidative stress parameters, including
malondialdehyde (MDA), glutathione (GSH) and total superoxide dismutase (tSOD) activity were
measured in GCF, before (day 0) and after treatment (7th and 30th day).
Antagonistically positioned healthy teeth were used as a control.
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