Drug Interaction Clinical Trial
Official title:
An Open-label, Randomized Study to Evaluate Pharmacokinetic Interaction, Pharmacodynamics and Safety After Multiple Oral Dosing of CJ-12420 and Amoxicillin/Clarithromycin in Healthy Subjects
Cohort 1
To evaluate the pharmacokinetic interactions of CJ-12420 after multiple oral doses of
CJ-12420 given alone or in combination with amoxicillin/clarithromycin in healthy subjects.
Cohort 2
To evaluate the pharmacodynamic profiles of CJ-12420 after multiple oral doses of CJ-12420
in combination with amoxicillin/clarithromycin in healthy subjects as compared to an active
control group, i.e., pantoprazole in combination with amoxicillin/clarithromycin.
To evaluate the pharmacokinetic the drug-drug interaction of CJ-12420 and amoxicillin/clarithromycin and investigate the pharmacodynamic of co-administration of CJ-12420 and amoxicillin and clarithromycin. ;
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