Pharmacokinetic Clinical Trial
Official title:
Multi-Centre, Open-Label, Two Segment, Parallel Group Study Comparing Plasma Pharmacokinetics of Ketoprofen in Diractin® Alone to Diractin® Applied Concomitant With Heat or Moderate Exercise
- Comparison of the plasma PK after single use of 100 mg ketoprofen from Diractin®. 50 mg
applied on 2 major joints to
- 400 mg ketoprofen from Diractin® (100 mg applied to 4 joints - overexposure)
- 100 mg and 400 mg ketoprofen from Diractin® used concomitant with heat application
- 100 mg and 400 mg ketoprofen from Diractin® used concomitant with moderate exercise
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label
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