Autism Spectrum Disorder Clinical Trial
Official title:
Neurocircuitry of Autism- fMRI and Transcranial Magnetic Stimulation Studies
This study uses functional brain imaging and noninvasive brain stimulation techniques to study the brain basis of developmental disorders like Autism Spectrum Disorder and Asperger Disorder. Functional magnetic resonance imaging (fMRI) and recently approved FDA treatment of depression, Transcranial magnetic stimulation (TMS) will be used to study the neurocircuitry of certain symptom clusters in developmental disorders.
The purpose of this research is to study areas of the brain that may have something to do
with repetitive movements (things that people do over and over again) and difficulty
communicating with other people (problems with talking to, understanding, or just being in a
relationships with other people). The investigators are trying to find out why these brain
areas are working differently in people with developmental disorders, such as Autism and how
the investigators can one day improve them with new brain stimulation techniques.
The investigators will do screening to make sure that you are eligible for the study. After
screening, the investigators will do functional MRI. In this procedure the subject or the
control will be looking at videos developed to understand their social communication and
language skills. The investigators will be able to understand differences of brain
activation between patients and control. The investigators will also use TMS to identify the
difference of motor excitability between patients and healthy control.
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