Clinical Trials Logo

Pertussis clinical trials

View clinical trials related to Pertussis.

Filter by:

NCT ID: NCT02040636 Completed - Hepatitis B Clinical Trials

Study of Tetanus and Diphtheria Toxoids Adsorbed Combined With Component Pertussis Vaccine and Inactivated Poliomyelitis

Start date: January 1999
Phase: Phase 2
Study type: Interventional

Primary objective: - To determine the safety and immunogenicity of tetanus and diphtheria toxoids adsorbed combined with component pertussis and inactivated poliomyelitis vaccine grown on vero cells (TdcP-IPV) compared to tetanus and diphtheria toxoids adsorbed combined with component pertussis and inactivated poliomyelitis vaccine grown on vero cells (TdcP-IPV) and Hepatitis B vaccine administered concurrently in adolescents 11-14 years of age. Secondary objective: - To determine whether concurrent administration of TdcP-IPV and Hepatitis B vaccines at 11-14 years of age results in detectable immunologic interactions between components of the two vaccines.

NCT ID: NCT02014519 Completed - Pertussis Clinical Trials

A Study to Determine the Seroprevalence of Bordetella Pertussis in Adults in Hungary

Start date: April 24, 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to perform an epidemiological survey of the adult population in Hungary to calculate the seroprevalence of pertussis.

NCT ID: NCT01993173 Completed - Tetanus Clinical Trials

Sanofi Pasteur's Tdap Combined Vaccine as a Booster Versus Local DT Vaccine in Children or Versus Local Td Vaccine in Adolescents and Adults in China.

Start date: November 2013
Phase: Phase 3
Study type: Interventional

The aim of the study is to assess the immunogenicity and safety profile of ADACEL compared to local adsorbed diphtheria and tetanus combined vaccine (local DT or local Td vaccine in participants in China. Primary objective: - To describe diphtheria and tetanus seroprotection rates and pertussis booster response rates induced by each of the study vaccines: ADACEL vaccine (in all study age groups), local DT vaccine (in children), and local Td vaccine (in adolescents and adults). Secondary Objectives: - To further describe in each group the immunogenicity of the study vaccines at baseline and 1 month after vaccination. - To describe the safety of the study vaccines

NCT ID: NCT01984125 Completed - Influenza Clinical Trials

Testing the Use of Prompts to Increase Adolescent Immunization Rates

AIMHi
Start date: April 2011
Phase: N/A
Study type: Interventional

Although most US adolescents visit their primary care doctor, their immunization rates are low. Primary care practices from two networks, one in upstate New York as well as a national network of pediatric clinics were surveyed to ask what they thought was the best strategy to increase immunization rates. Point-of-care prompts (either by an electronic health record message or by a nurse) when an adolescent patient comes in for any type of visit and is due for a vaccine was chosen. This study will determine if these prompts will increase immunization rates after a 12-month intervention period.

NCT ID: NCT01979588 Completed - Asthma Clinical Trials

How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice

WGA
Start date: November 2013
Phase: N/A
Study type: Interventional

Previous work has shown that the epidemiological context of a patient's presentation can provide important information for clinicians to aid in diagnosis and treatment. With current electronic health records, it is increasingly possible to perform syndromic surveillance that is local and specific to a patient's characteristics. The investigators have developed algorithms for syndromic surveillance for a number of conditions in which contextual information might be of use to treating clinicians. The syndromic surveillance algorithms already developed are for influenza-like-illness, whooping cough, asthma exacerbation, Group A Streptococcal pharyngitis, and gastroenteritis infection. The investigators plan on studying these tools with a clustered randomized control cohort study evaluating how clinical decision making is affected by use of these tools by outpatient general practitioners. The goal is to incorporate these validated algorithms into a quality improvement tool which will provide point-of-care clinical decision support to clinicians

NCT ID: NCT01933776 Completed - Tetanus Clinical Trials

Study of the Tdap Combined Vaccine (ADACELâ„¢) as a Booster Dose in Healthy Adults and Children in China

Start date: August 2013
Phase: Phase 1
Study type: Interventional

The aim of the study is to assess the safety profile of ADACEL vaccine in a small number of participants in China. Primary objective: - To describe the safety in terms of occurrence of serious adverse reactions and grade 3 adverse reactions after administration of Sanofi Pasteur's Tdap vaccine (ADACEL) given as a single dose in 20 adults and 20 children. Secondary objective: - To describe the full reactogenicity profile after administration of sanofi pasteur's Tdap vaccine (ADACEL) given as a single dose in 20 adults and 20 children.

NCT ID: NCT01917357 Completed - Hepatitis B Clinical Trials

A Comparison of the Immunogenicity and Safety of Quinvaxem in Mono-dose Vials and Uniject

Start date: September 2013
Phase: Phase 3
Study type: Interventional

This is a study to show that vaccination with three doses of Quinvaxem presented in Uniject is not inferior to vaccination with three doses of Quinvaxem presented in single dose vials, with respect to protection against all antibodies (anti-hepatitis B surface antibodies, anti-polyribosyl ribitol phosphate (PRP), anti-diphtheria, anti-tetanus and anti-Bordetella pertussis) one (1) month after completion of the 6-10-14 week vaccination course.

NCT ID: NCT01890447 Completed - Pertussis Clinical Trials

Assessing Contacts' Decision Making on Reducing the Risk of Pertussis Transmission to Newborns Through Immunisation

Start date: January 2015
Phase: N/A
Study type: Observational

This study aims to establish an effective method to inform parents or close relatives of newborns about the risk of pertussis transmission to newborns and the advantages offered by the cocooning strategy (vaccinating those who are in close contact with the newborn) by assessing the factors that affect the parents' decision-making to accept pertussis immunisation.

NCT ID: NCT01878435 Completed - Hepatitis B Clinical Trials

Randomized Controlled Trial of the Impact of Mobile Phone Delivered Reminders and Travel Subsidies to Improve Childhood Immunization Coverage Rates and Timeliness in Western Kenya

m-SIMU
Start date: October 2013
Phase: N/A
Study type: Interventional

The project goal is to conduct a randomized controlled trial (RCT) to test whether mobile phone short message system (SMS) reminders, either with or without mobile-phone based travel subsidies will improve timeliness, coverage, and drop-out rates of routine EPI vaccines in rural western Kenya.

NCT ID: NCT01761799 Completed - Influenza Clinical Trials

Protecting Pregnant Women From Infectious Diseases

Start date: December 2012
Phase: N/A
Study type: Interventional

The primary research aim of this project is to test the effectiveness of a comprehensive, evidence-based vaccine promotion package implemented in the obstetric setting on increasing the likelihood that a pregnant woman in Georgia will receive an influenza and/or pertussis vaccine.