18F-FDG PET/CT in Diagnostic Patients of Disorder of Consciousness

Persistent Vegetative State Clinical Trial

Official title:

18F-FDG PET/CT in Diagnostic Patients of Disorder of Consciousness

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02999490
• Other study ID #: HYXK0001
• Status: Completed
• Phase: N/A
• First received: March 25, 2016
• Last updated: April 19, 2018
• Start date: March 2016
• Est. completion date: December 5, 2017

Study information

• Verified date: April 2018
• Source: Guangzhou General Hospital of Guangzhou Military Command
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Clinical examinations are difficult to discriminate between vegetative state and minimally conscious state. the diagnostic and prognostic usefulness of neuroimaging methods has not been established in a clinical setting. we will do a forward study of PET imaging in disorders of consciousness patients, and validate with clinical assessments with the coma recovery Scale-Revised(CRS-R).

Description:

Every patient need to be conducted the PET/CT scanning two times.The first time is resting state.The second time is stimulated state by watching a vedio.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: December 5, 2017
• Est. primary completion date: December 1, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 10 Years to 75 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of disorder of consciousness

Exclusion Criteria:

Related Conditions & MeSH terms

• Consciousness Disorders
• Persistent Vegetative State

Intervention

Radiation:
• 18F-FDG
18F-FDG is positron emission tomography imaging agent which is already widely used in PET/CT examination.

Locations

Country	Name	City	State
China	The PET/CT Centre Guangzhou General Hospital of Guangzhou Military Command	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Guangzhou General Hospital of Guangzhou Military Command

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	standardized uptake value		60 mins after injecting 18F-FDG