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NCT04214340 Clinical Trial

Appendicitis in Adults and Children in France-A Prospective Study by the French Surgical Association Multicenter Cohort

Peritonitis Clinical Trial

— APPEA  

Official title:
Current Management of Appendicitis in Adults and Children in France-A Prospective Study by the French Surgical Association Multicenter Cohort (APPEA)

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04214340
Other study ID # AFC
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 1, 2016
Est. completion date March 23, 2017

Study information
Verified date December 2019
Source Association Francaise de Chirurgie
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Acute appendicitis still represents a surgical challenge, despite profound changes in practice in recent decades. The objective of this study was comprehensively document current surgical practices aimed at improving the management and follow-up of pediatrics and adults patients presenting with appendicitis in France.

Description:

The APPEA series is a national multicentric prospective cohort that included children and adults in France with acute appendicitis presenting between March 1st and June 30th, 2016. Data included demographic characteristics, medical history, symptoms, biology, radiology, treatments given during hospitalization, the modalities of the intervention, and any complications during a follow-up period of 6 months.

Recruitment information / eligibility
Status Completed
Enrollment 2285
Est. completion date March 23, 2017
Est. primary completion date June 30, 2016
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- patients admitted for appendicitis in participating centers

- informed

Exclusion Criteria:

- patient's (or parent's for children) opposition

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• evaluation of practices
Study of the management and follow-up of patients presenting with appendicitis in France.

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Association Francaise de Chirurgie

References & Publications (4)

Bhangu A, Søreide K, Di Saverio S, Assarsson JH, Drake FT. Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management. Lancet. 2015 Sep 26;386(10000):1278-1287. doi: 10.1016/S0140-6736(15)00275-5. Review. Erratum in: Lancet. 2017 Oct 14;390(10104):1736. — View Citation

Mak GZ, Loeff DS. Paradigm Shifts in the Treatment of Appendicitis. Pediatr Ann. 2016 Jul 1;45(7):e235-40. doi: 10.3928/00904481-20160525-01. Review. — View Citation

Teixeira FJR Jr, Couto Netto SDD, Akaishi EH, Utiyama EM, Menegozzo CAM, Rocha MC. Acute appendicitis, inflammatory appendiceal mass and the risk of a hidden malignant tumor: a systematic review of the literature. World J Emerg Surg. 2017 Mar 9;12:12. doi: 10.1186/s13017-017-0122-9. eCollection 2017. Review. — View Citation

Wagner M, Tubre DJ, Asensio JA. Evolution and Current Trends in the Management of Acute Appendicitis. Surg Clin North Am. 2018 Oct;98(5):1005-1023. doi: 10.1016/j.suc.2018.05.006. Epub 2018 Jul 13. Review. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Surgical practices in the management of adults and pediatrics patients with appendicitis Rate of laparoscopic surgery 6 months
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