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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT00516061
Other study ID # 2006-12-008
Secondary ID
Status Recruiting
Phase N/A
First received August 13, 2007
Last updated August 13, 2007
Start date December 2006
Est. completion date December 2007

Study information

Verified date December 2006
Source Samsung Medical Center
Contact Kyung Hoon Paik, M.D.
Phone 82-2-3410-1284
Email drwhite@skku.edu
Is FDA regulated No
Health authority South Korea: Institutional Review Board
Study type Observational

Clinical Trial Summary

Vascular endothelial growth factor(VEGF) appears to play a central role in the process leading to peritoneal angiogenesis and increased level of VEGF may contribute to high peritoneal small-solute transport rate (PSTR) in continuous ambulatory peritoneal dialysis (CAPD) patients in adult. In children, lymphatic absorption of solute is greater than adult. VEGF-C is related to lymphogenesis, but its role in peritoneal solute transport rate is not known. In this study, we evaluated possible relationship between dialysate VEGF and VEGF-C levels and PSTR in children.


Description:

There was significant correlation between dialysate VEGF165 and VEGF-C levels and significant correlation was noted between dialysate VEGF165 and PSTR. Interestingly, dialysate VEGF-C levels had significant correlation with PSTR. High PSTR seems to be related to elevated VEGF-C and VEGF.


Recruitment information / eligibility

Status Recruiting
Enrollment 40
Est. completion date December 2007
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 1 Year to 18 Years
Eligibility Inclusion Criteria:

- chronic renal failure

- children

- peritoneal dialysis

Exclusion Criteria:

- acute illness

Study Design

Observational Model: Defined Population, Time Perspective: Cross-Sectional


Related Conditions & MeSH terms


Locations

Country Name City State
Korea, Republic of Samsung Medical Center Seoul

Sponsors (1)

Lead Sponsor Collaborator
Samsung Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

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