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Peritoneal Carcinoma Metastatic clinical trials

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NCT ID: NCT04684459 Recruiting - Clinical trials for Pleural Effusion, Malignant

Dual-targeting HER2 and PD-L1 CAR-T for Cancers With Pleural or Peritoneal Metastasis

Start date: March 12, 2021
Phase: Early Phase 1
Study type: Interventional

Serosal cavity metastasis of malignant tumor is one of the late complications, which seriously affects the quality of life and survival time of patients. HER-2 is frequently expressed in breast cancer, ovarian cancer, lung cancer, gastric cancer and other malignant tumors. The HER-2/PD-L1 dual-targeting CAR-T will be investigated in patients with HER2 positive solid tumor serosal cavity metastases.