Peripheral Vascular Diseases Clinical Trial
Official title:
Follow-up Management of Peripheral Arterial Intervention With Clopidogrel MIRROR-Study
The Mirror Study is a randomized, double-blinded mono-centre trial the access the periinterventinal and postinterventional administration of clopidogrel in patients with peripheral vascular disease.
Clopidogrel is approved for secondary prevention of atherosclerosis in patients with
peripheral vascular disease. Currently there are no data about the amount of platelet
activation during peripheral arterial intervention, the effect of clopidogrel on platelet
adhesion and its clinical impact.
Patients with chronic peripheral arterial disease receive placebo or clopidogrel before the
intervention and for 6 months in follow-up. Platelet activation, the effect on macro-and
microcirculation will be assessed as well as clinical endpoints.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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