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Clinical Trial Summary

Untreated patients with Nodal T-follicular Helper (TFH) Cell Lymphoma will be treated with chidamide combined with azacitidine for four cycles. For patients with interim evaluation of CR, consolidation therapy with ASCT or another eight cycles with chidamide combined with azacitidine can be obtained. For patients with interim evaluation of PR, another two cycles of chidamide combined with azacitidine will be continued, followed by the second efficacy evaluation, and those who achieve CR receive consolidation therapy with ASCT or another six cycles of chidamide combined with azacitidine. Subsequently, chidamide was given as maintenance therapy for 12 months. Patients with SD or PD withdrew from this study.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05958719
Study type Interventional
Source Institute of Hematology & Blood Diseases Hospital
Contact Dehui Zou, Dr.
Phone 86-022-23909282
Email zoudehui@ihcams.ac.cn
Status Recruiting
Phase Phase 2
Start date March 2, 2023
Completion date March 2, 2027

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