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Chidamide Combined With PECM in Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

Peripheral T-cell Lymphoma Clinical Trial

Official title:
A Multicenter, Single-arm, Open II Phase Clinical Trial Evaluating the Efficacy of Chidamide Combined With Prednisone, Cyclophosphamide, Etoposide, and Methotrexate (PECM) in Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

Clinical Trial Summary

To observe the efficacy and safety of Chidamide combined with prednisone, cyclophosphamide, etoposide and methotrexate in relapsed or refractory PTCL.

Clinical Trial Description

Prednisone, cyclophosphamide, etoposide, and methotrexate regimens are derived from a "metronidazole, etoposide, procarbazine and cyclophosphamide (PEPC) regimen" regimen that differs from the traditional "maximal Tolerance "chemotherapy, and the use of low-dose chemotherapy, frequent drug therapy, the purpose is to anti-angiogenesis and reduce drug resistance. At present, the program in our treatment of relapsed or refractory PTCL patients effective, safe and controllable, but also look forward to other joint treatment, so as to achieve better curative effect. To provide new treatment options for such patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03321890
Study type Interventional
Source Sun Yat-sen University
Contact Zhiming Li, MD
Phone 86-20-87343765
Email lizhm@sysucc.org.cn
Status Recruiting
Phase Phase 2
Start date March 7, 2017
Completion date December 31, 2020
View Details
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