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Clinical Trial Summary

cross sectional observational study, aimed to assess the electrophysiological function of the motor units in liver cirrhotic patients.


Clinical Trial Description

Liver cirrhosis is a global health problem which could be associated with several neurological manifestations. The associated peripheral neuropathy could be assessed by conventional nerve conduction studies.

Objective: The study aims at early detection of peripheral neuropathy among patients of liver cirrhosis by conventional nerve conduction studies and quantitative EMG methods. In addition, the study aims at finding out correlation between peripheral neuropathy and severity of the liver cirrhosis.

Methods: This a cross-sectional study conducted on fifty-six liver cirrhotic patients, that had been recruited from the Endemic medicine department/outpatient clinics and their age-gender matched sixty-one healthy controls. The recruited patients were clinically assessed .Both conventional nerve conduction studies and quantitative EMG techniques in the form of MUNE calculation, using modified spike -triggered technique and IPA ratio evaluation were performed for the allocated cirrhotic patients. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04340999
Study type Observational
Source Kasr El Aini Hospital
Contact
Status Completed
Phase
Start date August 1, 2018
Completion date March 5, 2020

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