Frailty in Vascular Patients Undergoing Surgery

Status Recruiting

Clinical Trial Summary

An observational cohort study of the frailty of vascular surgery patients undergoing intervention and their outcomes.

Clinical Trial Description

Vascular surgical operations are major procedures with significant associated morbidity and mortality. Frailty is a major factor influencing surgical outcome, but the effect on morbidity/mortality and quality of life is poorly understood in vascular surgery. Activity levels play a significant role in frailty and in pre-intervention preparation. It is anticipated that as frailty levels increase, activity levels decrease. It is hypothesised that vascular surgery patients suffer from a high prevalence of frailty and that increasing frailty will lead to increased morbidity and mortality and decreased quality of life. This initial study will provide the foundations to identify targets for improvement in degree of frailty, appropriateness for surgery and outcome. This project aims to: Assess and quantify the prevalence of frailty as well as recording activity levels in the vascular surgery patient cohort Explore the impact of frailty and pre-op activity on surgical outcomes in the vascular surgical patient cohort to guide surgical treatments as well as future studies aimed at improving frailty and activity and thereby quality of life. Identification of an appropriate metric of frailty for this population group to include activity, is a secondary aim of this proposal. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03668821
Study type	Observational
Source	Imperial College London
Contact	Tristan R Lane, PhD FRCS
Phone	02033117317
Email	tristan.lane@imperial.ac.uk
Status	Recruiting
Phase
Start date	January 1, 2021
Completion date	October 1, 2025

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