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Aortoiliac Stenosis in Kidney Transplantation — TASC  

Peripheral Arterial Disease Clinical Trial

Official title:
Safety and Efficacy of Kidney Transplantation in Patients With Aortoiliac Stenosis

Clinical Trial Summary

The impact of aortoiliac stenosis on kidney transplant patients remains unclear. This study aims to investigate the safety and efficacy of kidney transplantation in patients with aortoiliac stenosis.

Clinical Trial Description

Kidney transplantation is the optimal treatment for end-stage renal disease (ESRD). Unfortunately, not all ESRD patients are eligible for kidney transplantation. Aortoiliac stenosis, an increasingly common type of peripheral arterial disease in ESRD patients, is considered as relative contra-indication for kidney transplantation. There are several reasons for concern, such as the complexity of the vascular anastomosis and inferior life expectancy. Consequently, it is still debated whether patients with aortoiliac stenosis would benefit from kidney transplantation. This study aimed to supplement current literature on the safety and efficacy of kidney transplantation in patients with aortoiliac stenosis. To achieve this, all patients undergoing kidney transplantation in Erasmus Medical Center between January 2010 and December 2020 were enrolled, and propensity score matching was used to minimize confounding factors. Additionally, long-term graft function was investigated to evaluate the impact of stenosis on graft function. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06020534
Study type Observational
Source Erasmus Medical Center
Contact
Status Completed
Phase
Start date January 1, 2022
Completion date June 30, 2023
View Details
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