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The Effects of Ramipril on Clinical Symptoms in Patients With Peripheral Arterial Disease

Peripheral Arterial Disease Clinical Trial

Official title:
The Effects of Ramipril on Clinical Symptoms in Patients With Peripheral Arterial Disease

Clinical Trial Summary

One important clinical challenge in older individuals is maintaining mobility in the absence of pain. Peripheral arterial disease affects up to 12% of adults over 50 and impairs quality of life due to intermittent claudication causing pain and limiting mobility.

Conventional therapies have only modest effect in improving symptoms. The investigators hypothesise that angiotensin converting enzyme inhibition (with ramipril), which causes arterial vasodilation, also improves clinical symptoms in patients with peripheral arterial disease.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00168467
Study type Interventional
Source Baker Heart Research Institute
Contact
Status Completed
Phase Phase 4
View Details
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