Clinical Trials Logo
  1. Home
  2. Perioperative Care
  3. NCT04852406

Protocol-based Management and Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy

Perioperative Care Clinical Trial

Official title:
Effect of Protocol-based Management on Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy: a Pragmatic Interventional Study

Clinical Trial Summary

The purpose of this pragmatic interventional study is to evaluate whether a protocol-based management of antithrombotic drugs can reduce a composite of perioperative outcomes in patients with chronic antithrombotic therapy before surgery.

Clinical Trial Description

Aging population and chronic medical disease make the management of surgical patients more complex. About one tenth of patients scheduled for surgery are taking antithrombotic medications. Coagulation disturbance induced by these medications may increase the risk of bleeding, whereas withholding these medications may increase the risk of thrombotic events. It is a dilemma when managing these patients. The guidelines and expert consensus published by multiple disciplinary teams constitute the perioperative antithrombotic management protocols. However, the effects of perioperative antithrombotic management guided by these guidelines or expert consensus are seldom reported. The investigators hypothesize that a protocol-based perioperative antithrombotic management can benefit patients with chronic antithrombotic therapy before surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04852406
Study type Interventional
Source Peking University First Hospital
Contact Hong Zhang, MD
Phone 86 10 83572784
Email zhanghong40@hotmail.com
Status Recruiting
Phase N/A
Start date April 21, 2021
Completion date January 2024
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT06043895 - EpiFaith CV for Central Venous Catheterization N/A
Completed NCT03308071 - Hypnosis for Symptom Management in Elective Orthopedic Surgery N/A
Not yet recruiting NCT03814681 - Postopoperarive Outcomes After Colorectal Surgery in Europe (euroPOWER)
Completed NCT03012802 - Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol
Completed NCT04724122 - Perioperative Care in Ethiopia
Completed NCT04037787 - ERAS (Enhanced Recovery After Surgery) Protocol Implementation in Piedmont Region for Colorectal Cancer Surgery N/A
Recruiting NCT06101641 - Effect of Shellac Nail Polish Application on Pulse Oximetry Measurements in Healthy Individuals N/A
Not yet recruiting NCT03864861 - Postoperative Outcomes Within an Enhanced Recovery After Bariatric Surgery Protocol
Not yet recruiting NCT03865810 - Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol in Gastric Surgery for Cancer
Completed NCT00994903 - Simvastatin in Colorectal Surgery Phase 3
Completed NCT04540315 - Reducing Surgical Readmissions Through Mobile Technology N/A
Not yet recruiting NCT06436560 - Support for Transgender and Non-Binary Individuals Seeking Vaginoplasty Study N/A
Completed NCT00911391 - Randomised Trial of Doppler-Optimised Fluid Balance in Elective Colectomy Phase 3
Completed NCT03325413 - Improvement of Perioperative Care of Elderly Patients N/A
Completed NCT04770259 - Pre-surgical Protocol for Frail Elderly People in Order to Reduce Hospitalization Days (APOPM). N/A
Completed NCT02580214 - Immunonutrition in Total Hip Arthroplasty Phase 2/Phase 3
Completed NCT01053169 - Observational Study of Prophylaxis and Treatment of Acute Perioperative Bleeding With Beriplex® P/N (Probe Study) N/A
Completed NCT01399814 - Restricted Intravenous Fluid Regime Effects on Immunological Indicators of Elderly Patients Operated for Abdominal Cancer Phase 3
Completed NCT00464529 - Accuracy and Safety of Real Time Continuous Glucose Monitoring Before, During and After Surgery N/A
Completed NCT05352698 - Validation of B-type Natriuretic Peptide With N-terminal Pro B-type Natriuretic Peptide in Perioperative Risk Assessment