Periodontal Disease Clinical Trial
Official title:
The Effect of an Antibiotic-antifungal Rinse on Periodontal Disease
Many physically handicapped patients at the dental department, Toronto Rehabilitation
Institute(TRI) have considerable gingival inflammation and breath odour because of the
inability to effectively handle a toothbrush. These patients have considerable periodontal
disease. There is a concern that these pathogens may have a detrimental effect on wound
healing in other areas of the body.
Hypothesis: Patients attending the dental department at TRI that are treated with the
antibiotic-antifungal rinse containing metronidazole and nystatin will show substantial
decrease in periodontal disease as measured by bleeding points and pocket depth when
compared to the group that continues to use their regular oral hygiene methods (control
group).
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
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