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Periodontal Disease clinical trials

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NCT ID: NCT02474498 Completed - Periodontal Disease Clinical Trials

EMD and/or Bone Substitute for the Treatment of Class II Furcations

Start date: March 2013
Phase: Phase 4
Study type: Interventional

To clinically evaluate the treatment of mandibular class II furcation defects with enamel matrix derivative (EMD) and/or a bone substitute graft make of beta tricalcium phosphate/hydroxyapatite (βTCP/HA).

NCT ID: NCT02463006 Completed - Periodontal Disease Clinical Trials

Porous and Non-porous Bone Grafts in Intra-bony Periodontal Defects

Start date: January 2014
Phase: Phase 2/Phase 3
Study type: Interventional

Till date, no study has been reported in the literature where porous bioactive glass was used for the management of periodontal osseous defects. In this context, the present study is designed to assess the efficacy of the porous variant of bioactive glass and compare with that of nonporous variant using cone beam computed tomography.

NCT ID: NCT02368678 Completed - Periodontitis Clinical Trials

"Study of Halitosis in Patients With Advanced Chronic Periodontitis"

HACP
Start date: April 2013
Phase: N/A
Study type: Interventional

The objective of this study was to evaluate whether short-term full mouth disinfection protocol could have a greater reduction in the levels of halitosis and volatile sulfur compound or not, when compared to quadrant-wise scaling and root planing

NCT ID: NCT02333227 Completed - Preterm Birth Clinical Trials

Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi

PPaX
Start date: May 1, 2015
Phase: N/A
Study type: Interventional

The hypothesis of the investigators' project is that comprehensive primary preterm birth prevention, inclusive of maternal oral health with xylitol chewing gum (the intervention), will reduce the rate of periodontal disease and caries, preterm birth prevalence, and neonatal mortality.

NCT ID: NCT02289066 Completed - Diabetes Mellitus Clinical Trials

Impact of Periodontal Disease on Outcomes in Diabetes

Start date: November 2013
Phase: N/A
Study type: Observational

This study examines how periodontal disease affects the complications of diabetes and how treatment for periodontal disease affects biomarkers associated with the complications of diabetes.

NCT ID: NCT02184962 Completed - Osteoporosis Clinical Trials

Periodontal Disease and Post-menopausal Osteoporosis

Start date: May 2012
Phase: N/A
Study type: Observational

The aim of this study was to investigate the levels of RANKL and Osteoprotegerin, and their relationship in gingival crevicular fluid of post-menopausal women with osteoporosis/osteopenia and chronic periodontitis simultaneously and evaluate the effect that the use of bisphosphonates in periodontal disease. Study hypothesis: "The osteoporosis / osteopenia in postmenopausal women patients with periodontal disease affect the ratio RANKL / OPG in gingival crevicular fluid samples favoring osteoclastogenesis processes "

NCT ID: NCT02180932 Completed - Periodontal Disease Clinical Trials

Towards a Viral Etiology of Periodontal Disease in Relation to Radiotherapy Treatment of Head and Neck Cancers

Start date: June 2014
Phase: N/A
Study type: Interventional

The treatment of otolaryngology (OLR) cancer is based on surgery, radiation, sometimes used in combination with chemotherapy. Patients treated with radiotherapy have multiple oral diseases: mucositis, hyposalivation, tissue fibrosis, exacerbation of periodontitis. Over 70% of patients with head and neck cancers treated with radiotherapy have a lower level of dental clinical attachment and 92% have loose teeth or missing. The management of these oral complications is a priority in OLR oncology. The aim is to improve the oral health of patients to achieve a comfortable life acceptable and necessary for healing. This project proposes to deepen the investigation with two main objectives: 1. To study in vivo the effect of radiation treatment on the evolution of the viral flora of the periodontium in a cohort of patients and matched controls. 2. To study in vitro the effects of irradiation on the replication EBV (herpesvirus) in producing websites lymphoepithelial tonsillar, and atypical dendritic cells associated with EBV that existence were recently discovered.

NCT ID: NCT02177591 Completed - Clinical trials for Coronary Artery Disease

Observational Study of the Association Between Periodontal Disease and Cardiovascular Disease

Start date: June 2014
Phase: N/A
Study type: Observational

The prevalence of cardiovascular disease is rising; new methods must be created to assess the cardiovascular status of patients. If cardiovascular disease can be predicted, it may facilitate prevention. An association between periodontal disease and cardiovascular has been established, but a definitive mechanism is not understood. A good first step in finding that mechanism is to look at the correlation between periodontal disease and cardiovascular disease, both of which have an inflammatory component. This study observes the level of cardiovascular disease in patients and correlates it with the presence and degree of periodontal pathogens.

NCT ID: NCT02126267 Completed - Clinical trials for Chronic Periodontitis

Evaluation of Techniques for Scaling and Root Planing and One Stage Full Mouth Disinfection

Start date: January 2013
Phase: N/A
Study type: Interventional

Evaluate and compare the effectiveness in a clinical and microbial perspective one stage full-mouth disinfection technique in relation to scaling and root planing per quadrant associated with chlorhexidine or azithromycin.

NCT ID: NCT02102360 Completed - Periodontal Disease Clinical Trials

Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial.

Start date: March 2012
Phase: Phase 4
Study type: Interventional

This clinical study compared a conventional surgical technique (CST) and a minimally invasive surgical technique (MIST) in the regenerative treatment of mandibular furcation defects.