Clinical Trials Logo
  1. Home
  2. Pericarditis
  3. NCT00128453

Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences

Pericarditis Clinical Trial

Official title:
Treatment and Prevention of Pericarditis With Colchicine. A Multicenter Double Blind Randomized Trial. The ICAP Trial: Investigation on Colchicine for Acute Pericarditis

Clinical Trial Summary

The purpose of the study is to determine whether colchicine is safe and effective in the treatment of acute pericarditis and the prevention of subsequent recurrences.

Clinical Trial Description

Colchicine is safe and effective in the management of recurrent pericarditis after failure of conventional treatment. Preliminary data have shown that it may be effective also in treatment of the index attack of pericarditis and the prevention of further recurrences.

Comparisons: The study will compare the safety and efficacy of colchicine in the treatment of acute pericarditis and the primary prevention of recurrences. Colchicine will be used in addition to conventional treatment. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00128453
Study type Interventional
Source Azienda Sanitaria Locale 3, Torino
Contact
Status Completed
Phase Phase 3
Start date August 2005
Completion date June 2012
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT03253315 - Management of Pericarditis in Children. N/A
Recruiting NCT02754713 - Prognostic Biomarkers in Patients With Acute Pericarditis N/A
Completed NCT00235079 - Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment. Phase 4
Completed NCT04906720 - Post-Ablation Pericarditis Reduction Study Phase 2
Not yet recruiting NCT05805930 - Therapeutic Approach in Colchicine-resistant Recurrent pEricarditis in Children Phase 3
Not yet recruiting NCT06411340 - Inflammation in Acute Cardiovascular Diseases - the CArdiovascular Inflammation Registry (CAIR)
Terminated NCT00946907 - Benign Acute Pericarditis: Brief Versus Longer Treatment Using Aspirin Phase 4
Not yet recruiting NCT05925790 - Clinical Phenotypes in Pericarditis: IL-1RA Antibodies and suPAR Levels
Recruiting NCT04294771 - JOint Use of Database to Identify Risk Factors of CARDio-vascular Toxicity Induced by Immune Checkpoint Inhibitors
Enrolling by invitation NCT04774549 - Inflammatory Cardiomyopathy Bern Registry
Completed NCT02083510 - Apolipoprotein CIII Reduction Via Colchicine Phase 0
Enrolling by invitation NCT01063582 - Noise, a Risk for Heart in Airplane Pilots N/A
Completed NCT04692766 - Study to Evaluate the Efficacy and Safety of RPH-104 Treatment in Patients With Idiopathic Recurrent Pericarditis Phase 2/Phase 3
Active, not recruiting NCT03231449 - A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa
Completed NCT00128414 - Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode) Phase 3
Recruiting NCT05046002 - COVID-19 Vaccine-induced Inflammatory Heart Disease Prevalence Registry
Recruiting NCT06103123 - MYocarditis and/or Pericarditis Following mRNA COVID-19 VACCination National Surveillance Study
Completed NCT01395082 - ACAM2000® Myopericarditis Registry