Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics — FTAA  

Complicated Appendicitis Clinical Trial

Official title: Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics

Status Recruiting

Clinical Trial Summary

Evaluate the application of the new therapeutic model post Fast Track surgery, in complicated acute appendicitis, in pediatric population on the rate of complications postoperative in the form of abdominal abscesses.

Clinical Trial Description

Complicated appendicitis is defined as the finding in the intraoperative study of a perforated, gangrenous or contaminated appendix with the presence of periappendicular abscess. In November 2005, the synthesis of an "Evidence-based clinical practice guide for acute appendicitis in pediatrics" at the Hospital Vall d'Hebron, the result of a committee of experts in the field. This protocol has been the guideline for our center in recent years.

Currently, the therapeutic approach is based on monotherapy antibiotic management (except for drug allergies, appendicular peritonitis, immunosuppression or nosocomial acquisition) in the postoperative period, with a minimum duration of 5 days (intravenous treatment). Therefore, the minimum hospital stay in these patients is expected to be equal to or more than 5 days.

Acute appendicitis represents the most frequent cause of acute abdomen in pediatric patients older than two years. It affects approximately 80,000 children in the European Union, making appendectomy one of the most frequent non-elective pediatric interventions performed by pediatric surgeons.

In recent years, several ambispective studies have been carried out at national level applying new therapeutic models that allow shortening the hospital stay by applying more lax discharge criteria and reducing the duration of intravenous antibiotic treatment, without significant alterations in the rate of postoperative complications.

By reducing hospital stay, the fast-track model not only brings clinical benefits to patients, but also economic benefits to the healthcare system. ;

Related Conditions & MeSH terms

• Appendicitis
• Complicated Appendicitis
• Laparoscopic Appendectomy
• Periappendicular Abscess

• NCT number: NCT05761080
• Study type: Interventional
• Source: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
• Contact: Carlos Leganes, MD
• Phone: +34935537635
• Email: cleganes@santpau.cat
• Status: Recruiting
• Phase: Phase 4
• Start date: April 22, 2021
• Completion date: December 2026