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Clinical Trial Summary

This clinical study will evaluate the effect of BioCeramic sealer with single cone compared with the control group treated with AH Plus with lateral condensation in root canal obturation on the healing of periapical lesions. The study sample will consist of 41 patients with 65 teeth with clear periapical lesions. Root canal obturation will be applied for all patients. BioCeramic sealer will be applied for the experimental group only. The changes of the dimensions of the periapical lesion will be assessed using CBCT radiographs; pre- and post- treatment changes for each group will be evaluated individually.


Clinical Trial Description

Periapical lesions is considered as the most common symptoms associated with infected root canals. Recently, the BioCeramic sealer has been considered one of the most common endodontic sealer that possess antibacterial properties, so it can have an effective role in the healing of periapical lesions, as well as its ability to prevent periapical leakage due to its attachment to the dentinal walls and gutta-percha cones. This study will evaluate the effect of BioCeramic sealer on the healing of periapical lesions and the changes of the dimensions of the lesions. Root canal obturation with gutta-percha cones will be applied in the two groups: The control group will receive the AH Plus with lateral condensation technique, and the experimental group will receive BioCeramic sealer with single cone technique. CBCT radiographs will be gotten before and after one year of the treatment to evaluate the periapical lesion dimensions changes. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06400030
Study type Interventional
Source Damascus University
Contact
Status Completed
Phase N/A
Start date June 22, 2020
Completion date April 15, 2023

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