Periapical; Infection Clinical Trial
Official title:
'A Comparison of Platelet Rich Fibrin & Mineralised Freezed Dried Bone Allograft to Radiographically Evaluate Healing Post Endodontic Surgery'- an In-vivo Study
Verified date | May 2020 |
Source | Saraswati Dental College |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
AIM: The aim of this study was to compare and evaluate the radiographic healing in patients undergoing apical surgery, using Freeze dried mineralized bone allograft and Platelet-rich Fibrin. OBJECTIVES: To evaluate radiographic healing after periapical surgery using Freeze dried mineralized bone allograft. To evaluate radiographic healing after periapical surgery using Platelet rich Fibrin. To compare the radiographic healing after periapical surgery using Freeze dried mineralized bone allograft and Platelet rich Fibrin. Method: Patients were selected(according to the inclusion criteria) and randomly allocated to PRF and Bone Graft groups.Following apicoectomy PRF gel and FDBA graft were prepared and placed in the osseous defect followed by placement of PRF membrane for graft stabilization and flap closure. Radiographic follow up was done at 1st, 3rd, 6th and 12th months for evaluation of healing using Molven Criteria.
Status | Completed |
Enrollment | 20 |
Est. completion date | December 9, 2019 |
Est. primary completion date | November 6, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 19 Years to 40 Years |
Eligibility |
Inclusion Criteria: - Adult teeth with failed conventional endodontic therapy and a need for periapical root end surgery. - Teeth with bony defect confined to periapical area. - Adult individuals presenting a tooth with persisting periapical radiolucency. - Adult individuals presenting a tooth with persistent fistula. - Adult individuals presenting a tooth with persisting symptoms after orthograde re-treatment. Exclusion Criteria: • Patients with severe systemic disorder (i.e. uncontrolled diabetes, immunologic diseases, malignancy), thrombocytopenia or insufficient compliance. |
Country | Name | City | State |
---|---|---|---|
India | Madhur Garg | Lucknow | Uttar Pradesh |
Lead Sponsor | Collaborator |
---|---|
Saraswati Dental College |
India,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in radiographic healing of periapical tissue after Apicoectomy | Two endodontists extraneous to the present study evaluated the radiographs post intervention and scored the healing according to Molven's scoring criteria for radiographic healing where 0 is representative of unsatisfactory healing and 3- complete healing | Change from Baseline radiographic score at 1 month | |
Primary | Change in radiographic healing of periapical tissue after Apicoectomy | Two endodontists extraneous to the present study evaluated the radiographs post intervention and scored the healing according to Molven's scoring criteria for radiographic healing where 0 is representative of unsatisfactory healing and 3- complete healing | Change from Baseline radiographic score at 3 months | |
Primary | Change in radiographic healing of periapical tissue after Apicoectomy | Two endodontists extraneous to the present study evaluated the radiographs post intervention and scored the healing according to Molven's scoring criteria for radiographic healing where 0 is representative of unsatisfactory healing and 3- complete healing | Change from Baseline radiographic score at 6 months | |
Primary | Change in radiographic healing of periapical tissue after Apicoectomy | Two endodontists extraneous to the present study evaluated the radiographs post intervention and scored the healing according to Molven's scoring criteria for radiographic healing where 0 is representative of unsatisfactory healing and 3- complete healing | Change from Baseline radiographic score at 12 months |
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