Escitalopram to Placebo in Patients With Localized Pancreatic Cancer

Status Terminated

Clinical Trial Summary

Use of antidepressants for participants with localized pancreatic and periampullary cancer receiving neoadjuvant therapy.

Clinical Trial Description

Anti-depressants have been shown to be beneficial in cancer participants. They reduce depressive symptoms and improve quality of life. Randomized trials have shown that antidepressants can reduce the development of depression in non-depressed participants with breast, melanoma, and head and neck cancers. It has been shown that treating depression can impact survival in cancer participants. Additionally, depressed pancreatic cancer participants have worse survival. Therefore, anti-depressants may also have implications for cancer treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05289830
Study type	Interventional
Source	Case Comprehensive Cancer Center
Contact
Status	Terminated
Phase	Phase 2
Start date	August 5, 2022
Completion date	August 27, 2023

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See also
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