Efficacy of Er: YSGG Laser in Treatment of Peri-implantitis

Status Completed

Clinical Trial Summary

Clinical Trial Description

This study will be carried out to evaluate the efficacy of Er: YSGG laser on oral biofilm removal from implant surface in various peri-implant defect morphology in the treatment of peri-implantitis as a primary objective. To assess the morphological changes and the biological response (biocompatibility) of implant surface after Er: YSGG laser therapy through Profilometer analysis and cell culture process to detect attachment, differentiation, and mineralization of Isolated rat Bone Marrow Mesenchymal stem cells (rBMMSCs) respectively as secondary objectives. The study was designed as an Ex Vivo study. Four periodontally and systemically healthy volunteers of both gender are included in this study for the formation of in vivo plaque biofilm. Each volunteer will wear a hard resin splint carrying six rough (machined implant; 3.3mm diameter, 8mm length) for 4 days to accumulate dental plaque naturally on the titanium surfaces of the implants. Therefore, 24 implants will be assessed for Er: YSGG laser therapy in different bone defect simulators. ;

Study Design

Related Conditions & MeSH terms

Peri-Implantitis

Clinical Trial Details

NCT number	NCT05137821
Study type	Interventional
Source	Ain Shams University
Contact
Status	Completed
Phase	N/A
Start date	August 10, 2023
Completion date	November 15, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05332327` - Comparison of the Accuracy of Different Periodontal Probes for Peri-implant Pocket Registration
Enrolling by invitation	`NCT06063876` - Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty	N/A
Completed	`NCT04249024` - Peri-implantitis, Comparing Treatments 970 nm Laser and Mucosal Flap Surgery	N/A
Withdrawn	`NCT03624257` - Comparing Two Treatment Modalities of Peri-implantitis - Blue Laser (445 nm) and Conventional Flap Surgery	N/A
Completed	`NCT03157193` - Effect of Hyaluronic Acid on Perimplantitis	Phase 4
Completed	`NCT03018795` - Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis	N/A
Completed	`NCT02375750` - Treatment of Peri-implantitis Lesions by Using Biomaterial	N/A
Enrolling by invitation	`NCT02575274` - Peri-Implantitis Surgical Treatment an RCT Study	Phase 2/Phase 3
Completed	`NCT04833569` - ICG-PDT, Periimplantitis, Diabetes Mellitus	Phase 1
Not yet recruiting	`NCT04337645` - Resective Surgical Treatment of Peri-implantitis.	N/A
Enrolling by invitation	`NCT06033859` - Incidence of Bleeding on Probing as an Indicator of Peri-Implant Disease Progression
Active, not recruiting	`NCT06390124` - Reconstructive Therapy of Peri-implantitis With PDGF-BB (Gem-21)	Phase 4
Enrolling by invitation	`NCT05675241` - Characterizing the Inflammation Around Dental Implants
Recruiting	`NCT04983758` - 20-year Implant Survival in Periodontally Healthy and Compromised Patients
Not yet recruiting	`NCT04323540` - Treatment of Peri-implantitis With or Without Simultaneous Soft Tissue Augmentation	N/A
Completed	`NCT04769609` - Reconstructive Surgical Therapy of Peri-implantitis
Completed	`NCT04874467` - Influence of Keratinized Mucosa on Dental Implants With Mucositis	N/A
Completed	`NCT05724706` - An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease
Completed	`NCT04559841` - Regenerative Surgical Treatment of Peri-implantitis Using Nanobone With or Without Simvastatin	N/A
Recruiting	`NCT05906810` - Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis	N/A