Peri-Implantitis Clinical Trial
Official title:
Comparing Two Treatment Modalities of Peri-implantitis - Blue Laser (445 nm) and Conventional Flap Surgery
A clinical trial comparing laser treatment and conventional mucosal flap surgery for treatment of peri-implantitis. The main aim of the study is to evaluate if treatment of peri-implantitis with a novel blue laser (445 nm) combined with scaling and root planning (SRP) is clinically comparable to conventional mucosal flap surgery in terms of pocket probing depth reduction.
The present project aims to evaluate a novel method in treating peri-implantitis, with focus
on decreasing the patient's suffering as well as disease progression. Peri-implantitis has a
direct influence on both physical and psychological well-being and have been related to
difficulty in chewing due to loss of implants, bad esthetic appearance as well as high costs.
Therefore, it is of importance for the individual as well as for the society to thoroughly
investigate any new treatment approaches.
The study is a prospective randomized clinical trial comparing laser treatment (test group)
and conventional mucosal flap surgery (active control group). Assessment of clinical
variables at baseline and after 6 months. Patient reported outcomes at baseline, directly
after treatment and after 10 days.
Primary Objective:
To evaluate if treatment of peri-implantitis with a novel blue laser (445 nm) combined with
scaling and root planning (SRP) is clinically comparable to conventional mucosal flap surgery
in terms of pocket probing depth reduction.
Secondary Objectives:
- To evaluate other clinical and radiological variables connected to peri-implantitis and
the inflammation surrounding the dental implant.
- To evaluate the patient experience of a novel blue laser for treatment of
peri-implantitis.
- To evaluate the inflammatory and microbial response after laser treatment
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05332327 -
Comparison of the Accuracy of Different Periodontal Probes for Peri-implant Pocket Registration
|
||
| Enrolling by invitation |
NCT06063876 -
Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
|
N/A | |
| Completed |
NCT04249024 -
Peri-implantitis, Comparing Treatments 970 nm Laser and Mucosal Flap Surgery
|
N/A | |
| Completed |
NCT03157193 -
Effect of Hyaluronic Acid on Perimplantitis
|
Phase 4 | |
| Completed |
NCT03018795 -
Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis
|
N/A | |
| Completed |
NCT02375750 -
Treatment of Peri-implantitis Lesions by Using Biomaterial
|
N/A | |
| Enrolling by invitation |
NCT02575274 -
Peri-Implantitis Surgical Treatment an RCT Study
|
Phase 2/Phase 3 | |
| Completed |
NCT04833569 -
ICG-PDT, Periimplantitis, Diabetes Mellitus
|
Phase 1 | |
| Not yet recruiting |
NCT04337645 -
Resective Surgical Treatment of Peri-implantitis.
|
N/A | |
| Enrolling by invitation |
NCT06033859 -
Incidence of Bleeding on Probing as an Indicator of Peri-Implant Disease Progression
|
||
| Active, not recruiting |
NCT06390124 -
Reconstructive Therapy of Peri-implantitis With PDGF-BB (Gem-21)
|
Phase 4 | |
| Enrolling by invitation |
NCT05675241 -
Characterizing the Inflammation Around Dental Implants
|
||
| Recruiting |
NCT04983758 -
20-year Implant Survival in Periodontally Healthy and Compromised Patients
|
||
| Not yet recruiting |
NCT04323540 -
Treatment of Peri-implantitis With or Without Simultaneous Soft Tissue Augmentation
|
N/A | |
| Completed |
NCT04874467 -
Influence of Keratinized Mucosa on Dental Implants With Mucositis
|
N/A | |
| Completed |
NCT04769609 -
Reconstructive Surgical Therapy of Peri-implantitis
|
||
| Completed |
NCT05724706 -
An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease
|
||
| Completed |
NCT04559841 -
Regenerative Surgical Treatment of Peri-implantitis Using Nanobone With or Without Simvastatin
|
N/A | |
| Recruiting |
NCT05906810 -
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
|
N/A | |
| Completed |
NCT05595746 -
Radiological Bone Loss on Different Levels of Dental Implants
|
N/A |