Efficacy of Diode Laser in Peri-implantitis

Peri-Implantitis Clinical Trial

Official title:

A Randomized Clinical Trial of an Adjunct Diode Laser Application in the Treatment of Peri-implantitis.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02362854
• Other study ID #: IstanbulU
• Status: Completed
• Phase: N/A
• First received: September 16, 2014
• Last updated: February 12, 2015
• Start date: February 2010
• Est. completion date: July 2014

Study information

• Verified date: February 2015
• Source: Istanbul University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Food and Drug Administration
• Study type: Interventional

Clinical Trial Summary

The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis. A prospective clinical, radiographic and microbiologic split-mouth study was conducted to test the following null hypothesis; adjunct application of a diode laser, in the conventional treatment of peri-implantitis, are not associated with a statistically significant difference regarding the microbial counts, marginal bone loss and peri-implant parameters.

Description:

Efficacy of a diode laser (DL) in peri-implantitis was investigated. 48 implants diagnosed with peri-implantitis were included. In addition to the conventional scaling and debridement, random 24 implants were lased by a DL. Periodontal indexes, microbiologic specimens and radiographs were used for assessment. Baseline parameters were similar between groups. After six months laser group revealed higher MBL than the control group. Microbiota of the implants were found unchanged after one month. DL appears to have no additional positive influence on the peri-implantitis treatment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: July 2014
• Est. primary completion date: July 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 years and older

• No local and systemic health problems prohibit the study interventions

• Bi-lateral implants with peri-implantitis diagnosis

Exclusion Criteria:

• Local and systemic health problems prohibiting the study interventions

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Alveolar Bone Loss
• Complications
• Implant
• Peri-Implantitis

Intervention

Procedure:
• Conventional peri-implantitis treatment
Elimination of the bacterial plaque. Establishing optimal healing conditions. Detoxification of the affected environment.

Device:
• DL application in peri-implantitis
Diode laser application in the diseased implants.

Locations

Country	Name	City	State
Turkey	Department of Oral Implantology, Faculty of Dentistry, Istanbul University	Istanbul	Capa

Sponsors (2)

Lead Sponsor	Collaborator
Istanbul University	Istanbul University Research Fund

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Peri-implant health indexes	Bleeding on probing, probing depth and plaque index which determined at the initiation of the study will be re-evaluated after one and six months to asees the effect of the variables	one and six months	No
Primary	Bacterial counts	Bacterial load around the the diseased implants will be determined at the initiation of the study. The assessment will be performed after one months	One month	No
Secondary	Marginal Bone loss	The marginal bone loss around the diseased implants will be assessed after six months to analyse any bone level change.	Six months	No

External Links

•   Department web link