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Peri-implant Mucositis clinical trials

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NCT ID: NCT05838365 Recruiting - Peri-Implantitis Clinical Trials

Immediate Versus Delayed Loading of Single Posterior Zirconia Implants

Start date: December 1, 2022
Phase: Phase 4
Study type: Interventional

The main aim of the present study is to investigate implant success rate after 5 years of function of immediate (Test group; within 7 days of implant placement) versus delayed (Control group; 8 weeks after implant placement) loading of two-pieces zirconia implant, placed in pristine bone without bone regeneration. Implant success rate will be defined according to Buser's criteria. Secondary endpoints: Marginal bone level (MBL) evaluation by means of standardized radiographs; Clinical evaluation of biological (e.g. Plaque Index, PI; Probing Pocket Depth, PPD, Bleeding on Probing, BOP; suppuration upon probing/palpation) and prosthetic/technical complications; Clinical evaluation of soft tissue width, keratinized tissue, marginal and interproximal soft tissue recession; Patient reported outcome measures (PROMs) by questionnaire administration:

NCT ID: NCT05834946 Active, not recruiting - Periodontitis Clinical Trials

Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis

Start date: March 4, 2021
Phase: N/A
Study type: Interventional

This prospective parallel, double-blind, four-arm randomised controlled clinical study is planned to assess the difference in the level of the inflammatory biomarkers expressed following the placement of the first dental implant in patients with history of periodontitis (successfully treated) and healthy controls without the disease, during implant osseointegration period. The subjects in both groups will also be randomised to receive one of the two types of implants provided which have different surface treatment.

NCT ID: NCT05810558 Completed - Clinical trials for Peri-implant Mucositis

Impact of Glycine Therapy on Peri-implant Mucositis

Start date: June 16, 2016
Phase: N/A
Study type: Interventional

The purpose of this research study is to determine the impact of glycine powder air-abrasive debridement (GPAD) on the microbiology of the tissues surrounding dental implants with health and inflammation (peri-implant mucositis).

NCT ID: NCT05804760 Completed - Peri-Implantitis Clinical Trials

Predictive Value of Reduced Keratinized Mucosa on the Secondary Prevention of Peri-implant Mucositis and Periimplantitis in Patients Attending Regular Supportive Peri-implant Care. A Longitudinal Analysis

Start date: February 12, 2020
Phase:
Study type: Observational

- Capture of the potential risk factor "lack of band of keratinised mucosa" over a period of up to 5 years. - Recording of peri-implant inflammatory processes in study participants that are not recorded during normal tooth cleaning - Registration of the extent of radiographic bone loss. Bone resorption through analysis of existing X-ray images - Individual therapy recommendation/individual supportive peri-implant care in case of peri-implant inflammation - The present study was specifically designed to investigate the effect of reduced width of keratinized mucosa (KM) on the secondary prevention of peri-implant mucositis and peri-implantitis in patients attending a supportive peri-implant care program (SPIC) over an observation period of up to five years.

NCT ID: NCT05801315 Completed - Clinical trials for Peri-implant Mucositis

Non-surgical Treatment of Peri-implant Mucositis: FMUD vs FMUD and Air-Flow Master Piezon®

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

The aim of the present study is to evaluate the adjunctive effect of glycine-powder air-polishing (GPAP) to full-mouth ultrasonic debridement (Fm-UD) in the treatment of peri-implant mucositis, and to determine the predictive role of implant and patient-level variables for disease resolution. Both treatments are described in the literature, but few studies are available on their comparison.

NCT ID: NCT05800795 Completed - Clinical trials for Peri-implant Mucositis

Evaluation of Soft Tissue Response to Titanium Healing Abutments Treated by Erbium: YAG Laser or Plasma Spray

Start date: June 20, 2021
Phase: N/A
Study type: Interventional

The attachment of peri implant soft tissue to the implant serves as a biological seal that can prevent the development of inflammatory peri-implant diseases. Presence of contaminants has been suggested to be associated with tissue damaging inflammation and titanium wear microparticles were demonstrated to activate osteoclastic action. Er: YAG laser has been extensively investigated clinically for applications for treating periimplantitis either independently or in combination with other techniques, showing favorable outcomes. Plasma spray treatment can decontaminate surfaces without modifying their topography. It is also able to increase the surface energy by obtaining more hydrophilic surfaces, which may increase the capacity of the titanium oxide layer to interact with cells and proteins of surrounding tissue improving cell adhesion to the treated surface.

NCT ID: NCT05772299 Completed - Clinical trials for Peri-implant Mucositis

Treatment of Inflammation Around Implants With a Laser or an Ultrasonic Device

Start date: August 31, 2021
Phase: N/A
Study type: Interventional

The goal of the clinical trial is to compare laser therapy with ultrasonic therapy in patients with inflammation in the tissue surrounding single implants (peri-implant mucositis). The outcomes are bleeding on probing (BOP), pocket depth, suppuration, recession of the peri-implant mucosal margin, the treatment time and changes in bone levels before and after treatment in the test, and control group respectively. The quality of life will be measured from a standardized protocol. The hypothesis is that treatment with laser therapy in patients with peri-implant mucositis will show less inflammation with less bleeding and a better pocket closure compared to the treatment with the ultrasound.

NCT ID: NCT05758103 Completed - Clinical trials for Peri-implant Mucositis

Limosilactobacillus Reuteri as an Adjuvant in the Treatment of Peri-implant Mucositis

LRRCT
Start date: January 5, 2022
Phase: N/A
Study type: Interventional

Mechanical debridement is the traditional method for the treatment of peri-implant mucositis and its success depends on the patient's correct oral hygiene. It is believed that probiotics may help by their ability to modulate the oral biofilm, resulting in anti-inflammatory and anti-bacterial plaque action. The aim of this study is to evaluate the adjuvant effect of the probiotic Limosilactobacillus reuteri in the mechanical treatment of peri-implant mucositis. This study aims to include 32 subjects with implant-supported total rehabilitation and peri-implant mucositis, divided into test and control groups, equally subjected to professional mechanical debridement, with the administration of a daily GUM® PerioBalance® lozenge for 30 days added to the test group. Plaque Index, Bleeding Index and probing pocket depth are evaluated before the intervention (baseline) and at 6 and 10 weeks later.

NCT ID: NCT05711576 Completed - Clinical trials for Peri-implant Mucositis

Impact of Smoking on the Effectiveness of Non Surgical Treatment of Peri-implant Mucositis

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

To evaluate the resolution of naturally occurring peri-implant mucositis (PM) treated by means of non-surgical mechanical debridement (NSMD) with or without full-mouth disinfection approach (FMD).

NCT ID: NCT05675241 Enrolling by invitation - Peri-Implantitis Clinical Trials

Characterizing the Inflammation Around Dental Implants

Start date: September 1, 2022
Phase:
Study type: Observational

The use of titanium dental implants has become a common modern treatment to restore teeth. Although the success rate of dental implants is high, inflammation around the dental implant still occurs. The current study will investigate if the inflammation around the implant is due to bacterial infection, hypersensitivity or both. The goal of this cross-sectional study is to (1) Establish the levels of cytokines in peri-implant crevicular fluid associated with bacterial infection and hypersensitivity reaction; (2) Compare the levels of cytokines associated with hypersensitivity and bacterial infection between healthy implants and inflamed implants (peri-mucositis and peri-implantitis); (3) Determine whether the difference in the levels of cytokines, if they exist, reflects the clinical diagnosis of healthy implants and inflamed implants.