Does Radial Artery Cannulation Affect the Perfusion Index(PI) of the Hand in Liver Transplant Operations?

Perfusion; Complications Clinical Trial

Official title:

Does Radial Artery Cannulation Affect the Perfusion Index of the Hand in Liver Transplant?

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06077396
• Other study ID #: LIVER TRANSP
• Status: Not yet recruiting
• Phase: N/A
• Start date: March 1, 2024
• Est. completion date: July 1, 2024

Study information

• Verified date: February 2024
• Source: Inonu University
• Contact: duygu demiroz
• Phone: 905319504421
• Email: drduygudemiroz[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

radial artery cannulation is performed by an experienced person, non-invasive blood pressure measurement will be made at 3 stages of the operation (dissection, anhepatic, neohepatic) and the effects of radial artery cannulation on the perfusion index will be evaluated by recording the correlation between radial artery and invasive measurements and the perfusion indexes of both hands simultaneously with Masimo.

Description:

Arterial lines placement is for real-time monitoring of blood pressures and arterial blood sampling in critically ill patients or those undergoing complex procedures and surgeries.

Routine monitoring will be performed after the patients are taken to the operating room. Before bilateral radial artery cannulation, allen test will be performed and entrance perfusion indexes will be checked. After radial artery cannulation is performed by an experienced person, non-invasive blood pressure measurement will be made at 3 stages of the operation (dissection, anhepatic, neohepatic) and the effects of radial artery cannulation on the perfusion index will be evaluated by recording the correlation between radial artery and invasive measurements and the perfusion indexes of both hands simultaneously with Masimo.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: July 1, 2024
• Est. primary completion date: June 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

Patients undergoing liver transplantation Patients who will undergo intraarterial cannulation

Exclusion Criteria:

Peripheral vascular diseases Prior upper extremity surgery Radial artery injury

Related Conditions & MeSH terms

• Arterial Catheterization, Peripheral
• Perfusion; Complications

Intervention

Procedure:
• radial artery cannulation
radial artery cannulation

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Inonu University

References & Publications (2)

Brzezinski M, Luisetti T, London MJ. Radial artery cannulation: a comprehensive review of recent anatomic and physiologic investigations. Anesth Analg. 2009 Dec;109(6):1763-81. doi: 10.1213/ANE.0b013e3181bbd416. — View Citation

Numaguchi A, Adachi YU, Aoki Y, Ishii Y, Suzuki K, Obata Y, Sato S, Nishiwaki K, Matsuda N. Radial artery cannulation decreases the distal arterial blood flow measured by power Doppler ultrasound. J Clin Monit Comput. 2015 Oct;29(5):653-7. doi: 10.1007/s10877-014-9648-5. Epub 2014 Dec 16. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	To evaluate the perfusion index of the hand in which artery cannulation was performed with Masimo.There is no result range	Arterial cannulation is mandatory for hemodynamic data monitoring in liver transplantation and is performed routinely. To evaluate the perfusion of the hand of the patients after cannulation	Intraoperative (patients during surgery)