Effects of Omega-3 Fish Oil Fat Emulsion on Rehabilitation and Immune Function After Radical Surgery Combined With Intraperitoneal Hyperthermic Infusion Chemotherapy in Patients With Locally Advanced Gastric Cancer

Stomach Neoplasms Clinical Trial

Official title: Effects of Omega-3 Fish Oil Fat Emulsion on Rehabilitation and Immune Function After Radical Surgery Combined With Intraperitoneal Hyperthermic Infusion Chemotherapy in Patients With Locally Advanced Gastric Cancer

Status Recruiting

Clinical Trial Summary

The purpose of this study was to investigate the effects of omega-3 fish oil fat emulsion on peripheral blood C-reactive protein, total lymphocyte count, plasma albumin and immune function after radical surgery combined with intraperitoneal hyperthermic perfusion chemotherapy in patients with locally advanced gastric cancer. at the same time, to explore the effects of omega-3 fish oil fat emulsion on complications, length of stay and total cost of hospitalization.

The main question it aims to answer is whether the use of omega-3 fish oil fat emulsion can improve patients' immunity, speed up recovery and reduce costs.

Participants will comprehensively collect patient-related baseline data, including sex, age, BMI, ASA grade, tumor location, histological grade, pathological tumor type, pTNM stage (AJCC cancer stage 8), and perilymphatic vascular / nerve infiltration.

Immune function evaluation related index: peripheral blood lymphocyte count. Plasma albumin concentration, C-reactive protein, postoperative infectious complications, length of stay and cost of hospitalization.

Finally, statistical analysis software was used to analyze the differences between the two groups, evaluate the above indicators and draw mutual conclusions.

Clinical Trial Description

The research process is as follows:

1. Select patients in the group according to the inclusion and exclusion criteria.

2. The patient signed the informed consent form

3. His system was used to collect patient data, including human-related baseline data, including sex, age, BMI, ASA grade, tumor location, histological grade, pathological tumor type, pTNM stage (AJCC cancer stage 8th edition), lymphatic vascular / nerve infiltration. Immune function evaluation related index: peripheral blood lymphocyte count. Plasma albumin concentration, C-reactive protein, postoperative infectious complications, length of stay and cost of hospitalization.

4. Using statistical software (SPSS) to judge the statistical difference.

5. It is concluded that the use value of omega-3 fish oil fat emulsion (Ewing) is evaluated. ;

Related Conditions & MeSH terms

• Chemotherapy Effect
• Immunisation Reaction
• Nutrition Aspect of Cancer
• Perfusion; Complications
• Stomach Neoplasms

• NCT number: NCT06047158
• Study type: Observational
• Source: The Affiliated Hospital of Qingdao University
• Contact: Liu Ruiqing, Doctor
• Phone: 18661809036
• Email: liuruiqing@smail.nju.edu.cn
• Status: Recruiting
• Start date: December 1, 2022
• Completion date: December 1, 2023