Opioid-sparing Effect of Intravenous Ibuprofen

Status Not yet recruiting

Clinical Trial Summary

The investigators aimed to evaluate tramadol-sparing effect of intravenous (IV) ibuprofen in patients undergoing percutaneous nephrolithotomy (PCNL).

Clinical Trial Description

Eighty patients who will undergoing PCNL are randomized to intravenous paracetamol (n=40) and intravenous ibuprofen (n=40) groups. Patients will receive 100 mL of physiologic saline with 1 g IV paracetamol or 800 mg IV ibuprofen 30 minutes before the end of the operation and postoperatively 6, 12 and 18 hours after PCNL in the paracetamol and ibuprofen groups, respectively. Patients in both groups will receive intravenous tramadol with patient controlled analgesia device (PCA).

The visual analog scale (VAS) will used to evaluate pain intensity scores in the postoperative period.

Total tramadol consumption, mean VAS score in the 1, 8 and 24 hours, demographic variables, operative variables, and side effects will record. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03016650
Study type	Interventional
Source	Inonu University
Contact	Muharrem Ucar, Asst.Prof.
Phone	+90 422 341 06 60
Email	umuharrem@hotmail.com
Status	Not yet recruiting
Phase	Phase 4
Start date	January 2017
Completion date	May 2017

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