Percutaneous Coronary Clinical Trial
Previous studies have shown that the transradial cardiac catheterization has decreased not
only bleeding complications related to the access site and procedural discomfort but also
morbidity and hospitalization as compared to transfemoral approach. At present, the right
radial approach (RRA) is the first choice routinely for coronary angiography and
interventions in daily clinical practice despite more marked subclavian artery tortuosity
than left radial approach (LRA). Although LRA has been thought to be more direct access to
the ascending aorta similar to transfemoral approach and may reduce fluoroscopy time and
cerebrovascular complications compared with RRA, the application of LRA for coronary
intervention is still low. Moreover, several studies have also obtained conflicting results
showing no difference in procedural success rate compared LRA and RRA using Judkins
catheters. To date, it remains unclear whether LRA is superior to RRA in term of safety and
feasibility for coronary angiography and interventions in real world practice and few data
of randomized control trial are available.
The aim of this study was to randomly investigate and compare the safety and feasibility of
LRA compared with RRA for coronary diagnostic angiography in Chinese subjects.
The investigators will enroll consecutively for 2 years all patients undergoing coronary
diagnostic procedures through trans radial approach.
The primary outcome was total procedural duration. Secondary outcomes included fluoroscopy
time, dose of radiation including cumulative air kerma and dose area product, contrast
volume and the incidence of vascular complications.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00808717 -
Efficacy of High Dose atorvaSTATIN Loading Before Primary Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction (STATIN STEMI)
|
Phase 4 |