Capsule Endoscopy for Hemorrhage in the Emergency Room

Status Not yet recruiting

Clinical Trial Summary

The researcher's primary hypothesis is that VCE allows for safe outpatient management of ED patients with suspected upper GI hemorrhage. A prospective multicenter randomized control trial was designed to investigate the safety of this approach.

Clinical Trial Description

The typical primary care, urgent care or emergency care provider is unable to evaluate common and serious conditions of the gastrointestinal tract such as a bleeding peptic ulcer. As such, more than 80% of patients who present to US ED's with suspected bleeding in their upper GI tract require hospitalization, procedural sedation by an anesthesiologist, and a traditional tube-based upper endoscopy by a gastroenterologist. While this traditional process is safe and effective, it is not efficient for our low-risk patients and not timely for our high-risk patients. The opportunity to bring Video Capsule Endoscopy to the front-lines of US medical care will revolutionize how we manage upper GI bleeding and shed light on critical diseases that have heretofore been hidden from most providers. This trial is an important step toward demonstrating that VCE is a safe and effective tool to risk-stratify upper GI bleeding and improve quality of emergency care for all patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01371591
Study type	Interventional
Source	George Washington University
Contact
Status	Not yet recruiting
Phase	N/A
Start date	April 1, 2018
Completion date	August 2018

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See also
Status	Clinical Trial	Phase
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Completed	`NCT00840008` - The Dissemination of Consensus Recommendations on Upper Gastrointestinal Bleeding	Phase 4
Terminated	`NCT00164905` - Role of Doppler Ultrasound in Severe Peptic Ulcer Hemorrhage	N/A
Completed	`NCT05563714` - Anticoagulation With Enhanced Gastrointestinal Safety	N/A
Completed	`NCT03362281` - Ilaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients	Phase 3
Completed	`NCT00164931` - A Study Comparing High Dose Omeprazole Infusion Against Scheduled Second Endoscopy for Bleeding Peptic Ulcer	Phase 3
Completed	`NCT04211194` - Registry for Upper Gastrointestinal Bleeding
Completed	`NCT01241266` - China Survey of Peptic Ulcer Bleeding	N/A
Completed	`NCT00037570` - Study Evaluating Pantoprazole in Peptic Ulcer Hemorrhage	Phase 2
Completed	`NCT00731601` - Intravenous Proton Pump Inhibitor for Peptic Ulcer Bleeding	Phase 4
Completed	`NCT05248321` - Precise Delivery of Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding	N/A
Recruiting	`NCT00687336` - Helicobacter Pylori Empiric Treatment in Ulcer Bleeding	Phase 4
Not yet recruiting	`NCT06273384` - Diagnostic Performance of CIM for Helicobacter Pylori Infection in Patients With Peptic Ulcer Bleeding
Terminated	`NCT00165009` - Resolution Endoclips Vs Epinephrine Injection and Heater Probe	Phase 3
Completed	`NCT03163680` - Efficacy of Low Dose of Proton Pump Inhibitor in Treatment Bleeding Ulcers
Completed	`NCT00279123` - Effects of 2 Different Doses of Pantoprazole on Gastric pH and Recurrent Bleeding in Patients Who Bled From Peptic Ulcers	Phase 4
Completed	`NCT03362268` - IIaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients	Phase 2
Completed	`NCT00573924` - Trial of Oral Versus Intravenous Proton Pump Inhibitor on Intragastric pH in Patients With Bleeding Ulcers	N/A
Withdrawn	`NCT02724150` - Comparison of Low Against High Regimen of Proton Pump Inhibitors for Treatment of Acute Peptic Ulcer Bleeding	Phase 4
Active, not recruiting	`NCT04536428` - ClearEndoclip Versus EZ Clip for Upper Gastrointestinal Ulcer Bleeding	N/A

Capsule Endoscopy for Hemorrhage in the Emergency Room — CHEER

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms