Clinical Trials Logo
  1. Home
  2. Penicillin Allergy
  3. NCT02036840
  4. Details
NCT02036840 Clinical Trial

Perioperative Antibiotic Choices for Surgical Prophylaxis in Penicillin-allergic Pediatric Patients

Penicillin Allergy Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02036840
Other study ID # IRB11-00822
Secondary ID
Status Completed
Phase N/A
First received January 13, 2014
Last updated April 20, 2015
Start date January 2013
Est. completion date November 2014

Study information
Verified date April 2015
Source Nationwide Children's Hospital
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Observational

Clinical Trial Summary

The proposed research project will retrospectively review the anesthetic records over the past 5 years and identify patients who present with a history of penicillin allergy or allergy to an antibiotic in the penicillin family. The reason for that history and the facts on which that allergy are noted will be determined. Additionally, the choice of antibiotic prophylaxis will be recorded and any adverse effect to that antibiotic noted. We will also note whether appropriate timing of the antibiotic is achieved.

Recruitment information / eligibility
Status Completed
Enrollment 513
Est. completion date November 2014
Est. primary completion date November 2014
Accepts healthy volunteers No
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Patients that are labeled as penicillin or penicillin family allergic.

Exclusion Criteria:

- As neurosurgical patients routinely receive vancomycin at NCH for surgical prophylaxis, they will be excluded from the study.

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Related Conditions & MeSH terms

Intervention

Drug:
• Antibiotic

Locations
Country Name City State
United States Nationwide Children's Hospital Columbus Ohio

Sponsors (1)
Lead Sponsor Collaborator
Joseph D. Tobias

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of Subjects With Antibiotic Related Adverse Event 24 hours No
See also
  Status Clinical Trial Phase
Terminated NCT05563610 - Oral Penicillin Challenge and Allergy De-labeling in Children Phase 4
Completed NCT05020327 - Inpatient Penicillin Allergy Delabeling Study Phase 4
Completed NCT04441021 - Feasibility Assessment of Risk Stratification and Oral Challenge in Hospitalized Children at Low Risk for Antibiotic Allergy
Not yet recruiting NCT05956080 - Penicillin Allergy Delabeling Among Surgical Patients N/A
Recruiting NCT03757052 - Amoxicillin Challenge for Penicillin Allergy Diagnosis N/A
Completed NCT03702270 - The Effect of Providing Stratification of Low Risk Penicillin Allergies on Penicillin Allergy Label Removal N/A
Recruiting NCT05464615 - Geisinger Antibiotic Allergy Pilot Program: Assess and Address Early Phase 1
Completed NCT03702283 - Effect of Providing Stratification of Low Risk Penicillin Allergies on Penicillin Allergy Label Removal in ICU Setting N/A
Not yet recruiting NCT03499457 - Penicillin Allergy in Shfayim Clinic N/A
Completed NCT01667055 - The Diagnosis of Beta-lactam Hypersensitivity in Thailand
Withdrawn NCT00589251 - Equivalency of Penicilloate Skin Test Reactivity Prepared by a Modified Alkaline Hydrolysis Technique N/A
Completed NCT04620746 - Penicillin Allergy Testing in STD Clinics Phase 4
Completed NCT05090527 - Penicillin Allergy Delabeling Project N/A
Completed NCT03033394 - Beta-lactam Pharmacokinetics in Secondary Care
Terminated NCT00363688 - Treating Patients With a History of Non-Life Threatening Allergic Reaction to Penicillin With Penicillin Phase 4
Completed NCT03158831 - Drug Challenges Without Prior Skin Testing Phase 1
Recruiting NCT06303128 - Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge Phase 3
Completed NCT03942731 - Penicillin Allergy Testing and Resensitization Rate
Completed NCT05010304 - Penicillin De-labeling in the Pediatric Primary Care Setting Phase 4
Completed NCT03404804 - Oral Challenge in the Pediatric ED Phase 4