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Pelvic Pain clinical trials

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NCT ID: NCT03199534 Completed - Pelvic Pain Clinical Trials

A Trial of Pelvic Floor Chemodenervation in Patients Undergoing Physical Therapy for High Tone Pelvic Floor Dysfunction

Start date: May 25, 2017
Phase: Phase 4
Study type: Interventional

This study assesses whether the addition of chemodenervation to an established regimen of pelvic floor physical therapy for painful high tone pelvic floor dysfunction improves patients' objective and subjective outcomes. Study subjects will select one of three treatment approaches: injection of 50 units Botulinum toxin A with local sedation as an office procedure, injection of 100u BoNTA-cosmetic in either the office or while anesthetized, or injection of 150 units Botulinum toxin A while anesthetized.

NCT ID: NCT03175809 Completed - Chronic Pelvic Pain Clinical Trials

Pelvic Floor Muscles Training Associated Dry Needling for Chronic Pelvic Pain

Start date: June 9, 2017
Phase: N/A
Study type: Interventional

The presence of trigger points in the pelvic floor musculature (PFM) is a frequent condition in individuals with chronic pelvic pain (CPP) and is associated with higher levels of pain, disability and functional decline. The purpose of this study is to test the effectiveness of two interventions: pelvic floor muscle (PFM) training with biofeedback and PFM training with the addition of trigger point dry needling applied over(Lumbar square, psoas, external obliques, gluteus medius, piriformis and adductors) on pain and quality of life of women with CPP.

NCT ID: NCT03167216 Completed - Clinical trials for Chronic Prostatitis With Chronic Pelvic Pain Syndrome

Mast Cells in Male Pelvic Pain and and Lower Urinary Tract Dysfunction

Start date: August 1, 2017
Phase: Early Phase 1
Study type: Interventional

The objective of this study is to evaluate inhibition of mast cells and the histamine 1 receptor (H1R) for treatment of chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS).

NCT ID: NCT03163160 Completed - Clinical trials for Musculoskeletal Pain

Electrolysis Technique vs Manual Therapy in Pelvic Pain

Start date: June 20, 2017
Phase: N/A
Study type: Interventional

Pelvic floor muscle physical therapy is recommended in clinical guidelines for women dyspareunia and pelvic pain. This study compare pelvic floor manual therapy and intratissue percutaneous electrolysis (EPI) technique in the treatment of pelvic pain in women with dyspareunia. Half of participants will receive pelvic floor manual therapy while the other half will receive intratissue percutaneous electrolysis technique.

NCT ID: NCT03126747 Completed - Clinical trials for Endometriosis and Dysmenorrhea

Drug Use Investigation (DUI) of YazFlex for Endometriosis-associated Pelvic Pain and/or Dysmenorrhea

Start date: June 29, 2017
Phase:
Study type: Observational

This study is a Japanese post-marketing surveillance (PMS) which is required by the regulatory authorities. General objective of PMS is to confirm the clinical usefulness, especially the safety profile of a drug under the routine clinical practice.

NCT ID: NCT03008382 Completed - Clinical trials for Myofascial Pelvic Pain

Interstitial Cystitis: Examination of the Central Autonomic Network

ICECAN
Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) afflicts 3 to 8 million women in the US. Symptoms of IC/BPS reduce quality of life, suppressing both social well-being and physical function. The chronic pain, voiding dysfunction, sleep deprivation and associated co-morbid conditions interfere with relationships and employment with significant direct (doctor visits, medication, surgery) and indirect (loss of productivity) economic impact, currently exceeding $100 million per year.This proposal aims to move the science of chronic pelvic pain (CPP) from simple associations towards an investigation of cause and effect relationships. The investigators will determine whether the striking changes in autonomic nervous system responsiveness (ANS-R) contribute meaningfully to the pathogenesis of IC/BPS.

NCT ID: NCT02961959 Completed - Low Back Pain Clinical Trials

Sacro-iliac Joint Arthrodesis or Non-operative Care for Treatment of Chronic Pelvic Pain. A Randomized Study.

Start date: October 2008
Phase: N/A
Study type: Interventional

Background: Pelvic pain is common during pregnancy and usually subsides after delivery. Some women, however, experience severe and long-standing pelvic pain, judged to emanate from the Sacro-iliac joints (SI-joints). Radiological correlates are absent and there are diverging opinions regarding the value of different clinical testing procedures and the use of anaesthetic blocks to reveal SI-joint origin of the pain. In case of slight or moderate pain the situation may be solved by the use of analgetics and physical therapy, but in case of severe pain the situation might end up in a discussion whether surgery with arthrodesis of the SI joint might be of value. To our knowledge, however, the results from surgical treatment has not been compared with non-surgical treatment in a randomized study. Aim: The investigators´ hypothesis is that 1. there exists a specific identifiable subgroup of patients within the chronic low back pain (CLBP) group in whom the pain emanates from the sacro-iliac (SI) joints, and that 2. patients in this subgroup may be selected based on thorough symptom analysis, and 3. that arthrodesis of the actual joint/s may reduce the pelvic pain. Methods: A RCT with parallel group design with pre- and post-treatment data. Inclusion of women 18-55 years old with pronounced pelvic pain for at least 2 years and having tried ordinary physical therapy without improvement and being on sick leave at least 50 percent. Operation by posterior approach with bone transplantation between the iliac bone and the sacrum, using microsurgical technique. Patients in both groups, the surgical (S) and non-surgical (NS) were all treated by formal physiotherapy at a five days stay at the Clinic and instructed to continue their training at home according to the lines given at the Clinic. Outcome: The primary outcome was perceived pelvic pain according to the assessments on the validated Balanced Inventory for Spinal Disorders questionnaire (BIS) and on a Visual Analogue Scale (VAS) before treatment and at follow-up one year after treatment. The perceived change in pain was also assessed on a transitional scale in the follow-up version of the BIS. Secondary patient reported outcome measures (PROM) were pain related functions assessed on the Oswestry Disability Index questionnaire (ODI), the BIS and the Roland-Morris questionnaire. Health related quality of life was assessed by using the Short-Form 36 (SF-36) and Euro-Quol (EQ-5D) questionnaires.

NCT ID: NCT02957214 Completed - Pelvic Pain Clinical Trials

Effects of an Intervention Program Based on Pain Education in Patients With Chronic Pelvic Pain

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to obtain imaging biomarkers based on changes in activity patterns and changes in brain connectivity obtained with the analysis of functional magnetic resonance imaging (fMRI) and tractography that are related to chronic pelvic pain

NCT ID: NCT02923245 Completed - Abdominal Pain Clinical Trials

POCUS Assessment of Bladder Fullness for Girls Awaiting Radiology-Performed Transabdominal Pelvic Ultrasound

Start date: September 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the accuracy and utility of point-of-care ultrasound (POCUS) of the bladder compared to patient's sensation of bladder fullness in predicting the ability to successfully perform a comprehensive transabdominal pelvic ultrasound in the pediatric Emergency Department (ED). We hypothesize that POCUS can more accurately and more quickly determine adequate bladder fullness to successfully perform transabdominal pelvic ultrasound than patient's perception of bladder fullness.

NCT ID: NCT02894151 Completed - Clinical trials for Clinically Diagnosed Endometriotic Patient Was Defined as a Woman Who Has Pelvic Pain and at Least One Evidence of PV or TVS

Effectiveness of Levonorgestrel-intrauterine System (LNG-IUS) Versus Depot Medroxyprogesterone Acetate (DMPA) in Treatment of Pelvic Pain in Clinically Diagnosed Endometriotic Patients

Start date: April 2015
Phase: Phase 2
Study type: Interventional

The primary objective : To compare effectiveness of pain control in endometriosis associated pelvic pain between LNG-IUS and DMPA The secondary objective : To compare vaginal bleeding pattern, side effect, continuation rate, satisfaction and quality of life between LNG-IUS and DMPA in treatment of endometriosis associated pelvic pain