Pelvic Organ Prolapse Clinical Trial
Official title:
Does Liposomal Bupivacaine Improve Pain Following Robotic Sacrocolpopexy and Rectocele Repair for Pelvic Organ Prolapse? A Randomized Placebo Controlled Trial
To determine if the injection of liposomal bupivacaine to laparoscopic port sites and rectocele repair incisions at the completion of a robotic sacrocolpopexy with concomitant rectocele repair will result in decreased postoperative pain compared to injection of placebo.
In the last 20 years, laparoscopic surgery has assumed an important role in gynecological
surgery. Unfortunately, patient surveys indicate there has been little improvement in the
incidence and severity of postsurgical pain in the past two decades. Postoperative pain is a
common complaint, occurring in 5-15% of patients and has been shown to significantly
contribute to overall patient dissatisfaction. It can lead to increased consumption of
opioids, with subsequent nausea, delayed bowel function, and prolonged postoperative
recovery. In an attempt to address pain related complications with port-site wounds, various
methods of pain control have been attempted. Currently, no standard of care exists and
management is based on surgeon and anesthesiologist preferences.
This study seeks to determine if the injection of liposomal bupivacaine to laparoscopic port
sites and rectocele repair incisions at the completion of a robotic sacrocolpopexy with
concomitant rectocele repair will result in decreased postoperative pain compared to
injection of placebo.
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