Pelvic Organ Prolapse Clinical Trial
Official title:
Effect of Pregnancy and Childbirth on the Pelvic Floor
Pelvic organ prolapse (POP) is one of the most common indications for gynaecological
surgery. In 1997, more than 225000 inpatient surgical procedures for POP were undertaken in
USA (22.7 per 10000 women) at an estimated cost of more than one billion dollars. In the UK,
the disorder accounts for 20% of the women on the waiting list for major gynaecological
surgery. Vaginal birth, advancing age and increasing body mass are the most consistent risk
factors. Furthermore a racial and congenital predisposition has been reported. The cause of
this disorder is likely to be multifactorial and attributable to a combination of factors,
varying from patient to patient.
Controversy exists as to whether the pregnancy per se rather than the mode of delivery
alters the risk of POP. Caesarean section appears to protect against the development of
prolapse. However, when a caesarean section is undertaken during the active stage of labour
it may not be completely protective. Ideally prospective longitudinal studies are needed to
study the impact of pregnancy and childbirth on pelvic organ prolapse. Unfortunately,
studies to date, are small with poor follow-up and have only assessed objective outcome
rendering it difficult to draw conclusions. The primary objective of our study was to
objectively assess the impact of pregnancy and childbirth on pelvic organ support using the
Pelvic Organ Prolapse Quantification (POPQ)System.
n/a
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
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