Platelet Rich Plasma in Levator Ani Muscle Trauma

Status Completed

Clinical Trial Summary

Levator trauma (ballooning) often occurs after vaginal delivery. Platelet rich plasma injection after delivery showed reduced hiatal area and maintain levator muscle strength.

Clinical Trial Description

This study aims to see if PRP has a beneficial effect on the repair of pelvic floor muscle damage in primipara. Therefore, this single-blinded randomized clinical trial compares the pelvic floor muscle repair in primipara following labor between the interventional group who received intramuscular PRP injection in levator ani muscle and the control group, as assessed by ultrasonography, perineometry. The ultrasonography outcome measures include lower hiatal area during Valsalva. The assessments are performed at multiple time points, which are before labor, 24-48 hours post-labor, 40 days post-labor, and 3 months post-labor. ;

Study Design

Related Conditions & MeSH terms

Pelvic Floor Disorders

Clinical Trial Details

NCT number	NCT03021954
Study type	Interventional
Source	Dr Cipto Mangunkusumo General Hospital
Contact
Status	Completed
Phase	Phase 2/Phase 3
Start date	November 2016
Completion date	January 2020

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03623880` - Enhancing Behavioral Treatment for Women With Pelvic Floor Disorders	N/A
Completed	`NCT05690555` - Pelvic Floor Physical Therapy vs Standard Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation	N/A
Not yet recruiting	`NCT06455150` - Prevalence of Pelvic Floor Dysfunctions in Female Badminton Athletes and Sedentary
Not yet recruiting	`NCT03456310` - Transperineal US on Basis of MRI in Female Pelvic Floor Dysfunction	N/A
Completed	`NCT01938092` - Vaginal Diazepam for the Treatment of Female Pelvic Pain	Phase 2
Completed	`NCT00884871` - Study of Surgically-Induced Weight Loss on Pelvic Floor Disorders	N/A
Completed	`NCT06014021` - Tele-rehabilitation for Female Athletes With Pelvic Floor Dysfunctions	N/A
Recruiting	`NCT05950633` - Postoperative Active Recovery	N/A
Not yet recruiting	`NCT05530681` - Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth	N/A
Completed	`NCT06206993` - Effects of Kieser Resistance Training Plus Kieser Pelvic Floor Training vs. Kieser Resistance Training Plus Traditional Pelvic Floor Exercise on Urinary Incontinence in Prostate Cancer Patients After Radical Prostatectomy	N/A
Recruiting	`NCT03683264` - Forceps vs Vacuum. Rate of Levator Ani Muscle Avulsion: Clinical Trial.	N/A
Active, not recruiting	`NCT04172519` - Pelvic Floor Muscles Training After Radical Prostatectomy.	N/A
Suspended	`NCT04544735` - Improving Women's Function After Pelvic Radiation	N/A
Completed	`NCT03715777` - Electromyographic Study for the Help and Guidance of BoNTA Administration in the Treatment of Chronic Pelvic Floor Pain	Phase 3
Completed	`NCT05127512` - Pelvic Floor Disorder Education in Prenatal Care	N/A
Completed	`NCT02259712` - Effectiveness of Hypopressive Exercises Versus Pelvic-perineal Physiotherapy	N/A
Completed	`NCT03714984` - The Efficacy of Pre-operative Educational Pelvic Floor Intervention on Urinary Continence	N/A
Not yet recruiting	`NCT05399901` - M-mode Ultrasonography in the Assessment and Treatment of Pelviperineal Dysfunctions (PerineUM)	N/A
Completed	`NCT05318768` - Association Between Physical Activity Level ，Overall Muscle Strength and Pelvic Floor Muscle Function in Women.
Completed	`NCT06193395` - Translation and Validation of the ICIQ-B in Danish	N/A