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Hormonal Status on Blood Flow and Tissue in Pelvic Organ Prolapse

Pelvic Floor Disorders Clinical Trial

Official title:
Role of Hormonal Status on Vascularization and Vaginal Tissue in Women With Pelvic Organ Prolapse

Clinical Trial Summary

Our primary aim in the current study is to determine important tissue differences, including muscle and connective tissue changes, between postmenopausal women and reproductive age women with pelvic floor dysfunction to help develop targeted and noninvasive treatments.

Clinical Trial Description

Our primary aim in the current study is to determine important tissue differences, including muscle and connective tissue changes, between postmenopausal women and reproductive age women with pelvic floor dysfunction to help develop targeted and noninvasive treatments. We will perform in vivo evaluations with colposcopy and OCT to determine epithelial thickness and overall mucosal health prior to surgery. At the time of surgery, we will obtain tissue for histologic and imaging analysis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01886794
Study type Interventional
Source The University of Texas Medical Branch, Galveston
Contact
Status Terminated
Phase Phase 4
Start date June 6, 2013
Completion date December 11, 2023
View Details
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