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Pediatric clinical trials

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NCT ID: NCT05776602 Recruiting - Brain Tumor Clinical Trials

Fast Brain MRI in Children With Suspected Brain Tumor

Fast MRI
Start date: May 1, 2023
Phase:
Study type: Observational

This study aims to assess the diagnostic performance of a new fast MRI sequence named Neuromix compared to routine clinical MRI for brain tumor in pediatric patients

NCT ID: NCT05737277 Not yet recruiting - Pediatric Clinical Trials

Gabapral in Pediatric IBS

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder (FGID) characterized by recurrent episodes of defecation related abdominal pain associated with abnormal bowel habit. Several studies have reported significant alterations in the gut microbiota that may promote the development and persistence of IBS. Some Bifidobacterium species, mainly Bifidobacterium adolescentis, have a documented immunomodulatory effect and can modulate visceral hypersensitivity or improve the integrity of the intestinal epithelium barrier thorough its well-known ability to produce g-aminobutyric acid Thus, designed a randomised, double-blind, placebo-controlled, parallel-arm study evaluating the efficacy and safety of Bifidobacterium adolescentis PRL2019 on abdominal pain symptoms in pediatric patients with Irritative bowel sindorom

NCT ID: NCT05670756 Enrolling by invitation - Surgery Clinical Trials

Preoperative Survey to Evaluate Patient Allergy

Start date: May 1, 2023
Phase:
Study type: Observational

The study will only involve identification of the listed allergies from the electronic medical record and investigation into the symptoms that prompted this allergy listing. The purpose is to evaluate demographics and prevalence of allergies in patients presenting for surgery, evaluate the medical decision making process behind allergy identification, and determine its potential impact on perioperative care. The participants will be asked to complete a survey in REDCap using an iPad during the visit.

NCT ID: NCT05670262 Recruiting - Pediatric Clinical Trials

The Roles of Human Microbiome and Vitamin D in the Development of Childhood Allergic Diseases

Start date: August 4, 2022
Phase:
Study type: Observational

A birth cohort study to evaluate the role of human microbiome and vitamin D in the development of allergic diseases in young child before one year of age.

NCT ID: NCT05584683 Recruiting - Clinical trials for Bacterial Infections

A Pharmacokinetic Study of LP-001 in Children With a Bacterial Infection

Start date: August 9, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the pharmacokinetic profiles of LP-001, an amoxicillin and clavulanate formulation, for use in pediatric patients with a bacterial infection.

NCT ID: NCT05511233 Not yet recruiting - Pediatric Clinical Trials

ERAS Protocol in Newborns: CARES Study

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Aim: To determine whether the enteral feeding time and the type of the nutrient (according to the ERAS Recommendations) have any effect on LoS, complications, body weight gain, time until oral feeding, and time until first stool who have undergone intestinal surgery. Design: A blinded, retrospective, randomized controlled trial. Setting: One-centred. Participants: Newborns who had intestinal surgery in the Ege University Faculty of Medicine Hospital Neonatal Surgery Intensive Care Unit and whose records can be accessed retrospectively from the electronic health records will be included. Those whose early enteral feeding initiation is contraindicated will not be included in the study.

NCT ID: NCT05474131 Completed - Cardiac Arrest Clinical Trials

Pediatric Out-of-hospital Cardiopulmonary Arrest

Ped-CPA
Start date: January 1, 2019
Phase:
Study type: Observational

The objective of this observational and retrospective study is to determine the predictive factors of in-hospital mortality following an out-of-hospital cardiopulmonary arrest (CPA) in the population under 18 years old. Data are collected from telephone calls and medical regulation records processed by the health call center of 2 french departments between January 1, 2019, and March 15, 2022. The medical records of the included patients will also be reread in order to obtain the patient's status at 30 days after the CPA. Detailed description: The literature reports numerous works evaluating the epidemiological characteristics of pediatric out-of-hospital cardiorespiratory arrest. An improvement in survival has been reported in the case of resuscitation guided by the operator in medical regulation before the arrival of the emergency services. Indeed, the regulation phase at the 15 center in France is of fundamental importance. Recent evolutions, notably with the creation of specific call-taking professions, show the importance attached to improving practices. The population concerned is characterized by children under 18 years of age, victims of an extra-hospital cardiorespiratory arrest. It is a retrospective study over three years and three months, multicentric, from the emergency service (SAMU) 57 and 69. The primary endpoint was the all-cause mortality at thirty days of the admission. The case report form (CRF) will collect the main aspects of telephone management at the 15 centers, out-of-hospital management by the emergency teams, and the personal characteristics of the emergency physicians and out-of-hospital responders (gender, age, family situation, etc.). The medical management in the emergency department and the first stages of in-hospital management will also be analyzed. The patients included who are still alive will receive a notification of non-objection by mail.

NCT ID: NCT05453968 Active, not recruiting - Pediatric Clinical Trials

Berotralstat Treatment in Children With Hereditary Angioedema

APeX-P
Start date: October 25, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics (PK) and safety of berotralstat to determine the appropriate weight-based dose for pediatric participants 2 to < 12 years old for prophylactic treatment to prevent attacks of hereditary angioedema (HAE).

NCT ID: NCT05371678 Recruiting - Pediatric Clinical Trials

Comparison of Two Intervention in Children With Functional Constipation

Start date: April 18, 2022
Phase: N/A
Study type: Interventional

The purpose of this study; to compare the effects of therapeutic motor control interventions and conventional treatment in children with functional constipation on symptoms, spinal posture and mobility and trunk muscles endurance.

NCT ID: NCT05362279 Not yet recruiting - Pediatric Clinical Trials

The Effect of Education on Nurses' Knowledge About High-flow Nasal Cannula Oxygen Therapy

Start date: May 10, 2022
Phase: N/A
Study type: Interventional

This study was conducted to evaluate the oxygen therapy methods used in pediatric services and to specify the roles and responsibilities of nurses in the application of HFNC, which is one of these methods. Although the decision to implement this treatment method is under the responsibility of the physician in Turkey, the use of the device, observing the effectiveness of the treatment, monitoring and recording the changes in the vital signs of the children are under the responsibility of the nurses shows the importance of the nursing perspective on HFNC.