Tracheal Suctioning With or Without Expiratory Pause Maneuver in Children

Status Recruiting

Clinical Trial Summary

The purpose of this study is to evaluate the efficacy of tracheal suctioning associate with expiratory pause maneuver in children on invasive mechanical ventilation.

Clinical Trial Description

After being informed about the study and potential risks, all parents or guardians giving written informed consent will be evaluate for study entry. Children in invasive mechanical ventilation who meet eligibility criteria will be submitted of two techniques of tracheal suctioning (with and without expiratory pause maneuver), randomized in a crossover trial in a 1:1 ratio, for determine the first technique to be applied. Clinical data will be collected (sex, age, presence of previous disease, diagnosis of hospitalization), as well as the ventilatory parameters (ventilation mode, peak inspiratory pressure, positive end-expiratory pressure, tidal volume, respiratory frequency, fraction of inspired oxygen). The protocol consists of an initial conventional tracheal suctioning with a negative pressure of 40mmHg for all the participants. After two (2) hours the first technique will be applied and an interval of another two hours for the application of the second technique. Respiratory mechanics and hemodynamic parameters will be evaluate before and after 30 minutes of each tracheal suctioning techniques. In case of clinical alterations that may aggravate the patients condition during the protocol (oxygen saturation < 85%, heart rate > 190bpm and/or decrease 20% of mean arterial blood pressure), the technique will be interrupted immediately and the patient will be evaluated. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05805475
Study type	Interventional
Source	Hospital de Clinicas de Porto Alegre
Contact	Bruna Ziegler
Phone	+5551 3359-7333
Email	bziegler@hcpa.edu.br
Status	Recruiting
Phase	N/A
Start date	April 1, 2023
Completion date	March 31, 2024

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05030337` - Optimising Ventilation in Preterms With Closed-loop Oxygen Control	N/A
Completed	`NCT05144607` - Impact of Inspiratory Muscle Pressure Curves on the Ability of Professionals to Identify Patient-ventilator Asynchronies	N/A
Recruiting	`NCT03697785` - Weaning Algorithm for Mechanical VEntilation	N/A
Completed	`NCT05084976` - Parental Perception of COVID-19 Vaccine in Technology Dependent Patients
Active, not recruiting	`NCT05886387` - a Bayesian Analysis of Three Randomised Clinical Trials of Intraoperative Ventilation
Completed	`NCT04429399` - Lowering PEEP: Weaning From High PEEP Setting	N/A
Completed	`NCT02249039` - Intravenous Clonidine for Sedation in Infants and Children Who Are Mechanically Ventilated - Dosing Finding Study	Phase 1
Recruiting	`NCT02071524` - Evaluation of the Effects of Fluid Therapy on Respiratory Mechanics	N/A
Completed	`NCT01114022` - Prevention Inhalation of Bacterial by Using Endotracheal Tube Balloon Polyvinyl Chloride or Polyurethane	N/A
Completed	`NCT00893763` - Strategies To Prevent Pneumonia 2 (SToPP2)	Phase 2
Terminated	`NCT05056103` - Automated Secretion Removal in ICU Patients	N/A
Active, not recruiting	`NCT04558476` - Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation	Phase 2
Recruiting	`NCT05295186` - PAV Trial During SBT Trial
Active, not recruiting	`NCT05370248` - The Effect of 6 ml/kg vs 10 ml/kg Tidal Volume on Diaphragm Dysfunction in Critically Mechanically Ventilated Patient	N/A
Completed	`NCT04589910` - Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound.	N/A
Completed	`NCT04818164` - Prone Position Improves End-Expiratory Lung Volumes in COVID-19 Acute Respiratory Distress Syndrome
Completed	`NCT04193254` - LPP , MP and DP:Relation With Mortality and SOFA in Mechanically Ventilated Patients in ER, Ward and ICU
Not yet recruiting	`NCT03259854` - Non Invasive Mechanical Ventilation VERSUS Oxygen MASK	N/A
Completed	`NCT06332768` - NIV Versus HFO Versus Standard Therapy Immediately After Weaning From Mechanical Ventilation in ARDS Patients	N/A
Not yet recruiting	`NCT03245684` - Assisted or Controlled Ventilation in Ards (Ascovent)	N/A